U-PLEX Diabetes Combo 1 (rat)

Analyte	LLOD - ULOD	units
C-Peptide	220 - 125,000	pg/mL
GLP-1 (total)	0.59 - 576	pM
Glucagon	0.13 - 156	pM
Insulin	3.0 - 5,500	μIU/mL
Leptin	11 - 50,000	pg/mL
PYY (total)	1.1 - 4,000	pg/mL

Application(s)		Metabolic
Analyte(s)		C-Peptide, GLP-1 (total), Glucagon, Insulin, Leptin, PYY (total)
Species		Rat
Instrument(s)		SECTOR Imager 2400 , SECTOR Imager 6000 , MESO QuickPlex SQ 120 , MESO QuickPlex SQ 120MM , MESO SECTOR S 600 , MESO SECTOR S 600MM
U-PLEX Group Compatibility		Metabolic Group 1
Plate Type		96-well
Sample Type		Cell Culture Media, EDTA Plasma, P800 Plasma, Serum
Usage Statement		For Research Use Only. Not for use in diagnostic procedures.
Storage Condition		Multi-Component
Schedule B Code		3822.19.0000

Kit Contents for Catalog No. K15309K-1

Product Description

Storage

Quantity per Kit

Rat Diabetes Combo 1, Box 1 of 2 (1 PL)

Multi-Component

1 each
(1 plate size)

U-PLEX Linker Set, 3-Assay (300 µL)	2-8 °C	1 each (1 vial)
U-PLEX Mouse/Rat PYY (total) Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX Mouse/Rat C-Peptide Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX GLP-1 (total) Antibody Set	2-8 °C	1 each (1 plate size)
Calibrator 18	2-8 °C	1 vial (1 vial)
U-PLEX 3-Assay, 96-Well SECTOR Plate	2-8 °C	1 each (1 plate)
U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)
Diluent 11	≤-10 °C	1 bottle (10 mL)
Diluent 13	≤-10 °C	1 bottle (10 mL)
MSD GOLD Read Buffer B	RT	1 bottle (18 mL)
Aprotinin	2-8 °C	1 vial (50 μL)
MSD Blocker D-R	≤-10 °C	1 vial (0.2 mL)

Rat Diabetes Combo 1, Box 2 of 2 (1 PL)

Multi-Component

1 each
(1 plate size)

U-PLEX Linker Set, 3-Assay (300 µL)	2-8 °C	1 each (1 vial)
U-PLEX Mouse/Rat Leptin Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX Mouse/Rat Insulin Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX Glucagon Antibody Set	2-8 °C	1 each (1 plate size)
Calibrator 19	2-8 °C	1 vial (1 vial)
U-PLEX 3-Assay, 96-Well SECTOR Plate	2-8 °C	1 each (1 plate)
U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)
Diluent 11	≤-10 °C	1 bottle (10 mL)
Diluent 13	≤-10 °C	1 bottle (10 mL)
MSD GOLD Read Buffer B	RT	1 bottle (18 mL)
Aprotinin	2-8 °C	1 vial (50 μL)
MSD Blocker D-R	≤-10 °C	1 vial (0.2 mL)

Kit Contents for Catalog No. K15309K-2

Product Description

Storage

Quantity per Kit

Rat Diabetes Combo 1, Box 1 of 2 (5 PL)

Multi-Component

1 each
(5 plate size)

U-PLEX Linker Set, 3-Assay (1.8 mL)	2-8 °C	1 each (1 vial)
U-PLEX Mouse/Rat PYY (total) Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX Mouse/Rat C-Peptide Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX GLP-1 (total) Antibody Set	2-8 °C	1 each (5 plate size)
Calibrator 18	2-8 °C	5 vial (1 vial)
U-PLEX 3-Assay, 96-Well SECTOR Plate	2-8 °C	5 each (1 plate)
U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)
Diluent 11	≤-10 °C	1 bottle (50 mL)
Diluent 13	≤-10 °C	1 bottle (50 mL)
MSD GOLD Read Buffer B	RT	1 bottle (90 mL)
Aprotinin	2-8 °C	1 vial (250 μL)
MSD Blocker D-R	≤-10 °C	1 vial (1 mL)

Rat Diabetes Combo 1, Box 2 of 2 (5 PL)

Multi-Component

1 each
(5 plate size)

U-PLEX Linker Set, 3-Assay (1.8 mL)	2-8 °C	1 each (1 vial)
U-PLEX Mouse/Rat Leptin Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX Mouse/Ra Insulin Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX Glucagon Antibody Set	2-8 °C	1 each (5 plate size)
Calibrator 19	2-8 °C	5 vial (1 vial)
U-PLEX 3-Assay, 96-Well SECTOR Plate	2-8 °C	5 each (1 plate)
U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)
Diluent 11	≤-10 °C	1 bottle (50 mL)
Diluent 13	≤-10 °C	1 bottle (50 mL)
MSD GOLD Read Buffer B	RT	1 bottle (90 mL)
Aprotinin	2-8 °C	1 vial (250 μL)
MSD Blocker D-R	≤-10 °C	1 vial (1 mL)

Kit Contents for Catalog No. K15309K-4

Product Description

Storage

Quantity per Kit

Rat Diabetes Combo 1, Box 1 of 2 (25 PL)

Multi-Component

1 each
(25 plate size)

U-PLEX Linker Set, 3-Assay (1.8 mL)	2-8 °C	5 each (1 vial)
U-PLEX Mouse/Rat PYY (total) Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX Mouse/Rat C-Peptide Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX GLP-1 (total) Antibody Set	2-8 °C	5 each (5 plate size)
Calibrator 18	2-8 °C	25 vial (1 vial)
U-PLEX 3-Assay, 96-Well SECTOR Plate	2-8 °C	25 each (1 plate)
U-PLEX Stop Solution	2-8 °C	5 bottle (40 mL)
Diluent 11	≤-10 °C	5 bottle (50 mL)
Diluent 13	≤-10 °C	5 bottle (50 mL)
MSD GOLD Read Buffer B	RT	5 bottle (90 mL)
Aprotinin	2-8 °C	5 vial (250 μL)
MSD Blocker D-R	≤-10 °C	5 vial (1 mL)

Rat Diabetes Combo 1, Box 2 of 2 (25 PL)

Multi-Component

1 each
(25 plate size)

U-PLEX Linker Set, 3-Assay (1.8 mL)	2-8 °C	5 each (1 vial)
U-PLEX Mouse/Rat Leptin Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX Mouse/Ra Insulin Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX Glucagon Antibody Set	2-8 °C	5 each (5 plate size)
Calibrator 19	2-8 °C	25 vial (1 vial)
U-PLEX 3-Assay, 96-Well SECTOR Plate	2-8 °C	25 each (1 plate)
U-PLEX Stop Solution	2-8 °C	5 bottle (40 mL)
Diluent 11	≤-10 °C	5 bottle (50 mL)
Diluent 13	≤-10 °C	5 bottle (50 mL)
MSD GOLD Read Buffer B	RT	5 bottle (90 mL)
Aprotinin	2-8 °C	5 vial (250 μL)
MSD Blocker D-R	≤-10 °C	5 vial (1 mL)

Product Inserts		U-PLEX Metabolic Group 1 (rat) Multiplex Insert
Datasheets		U-PLEX Rat C-Peptide U-PLEX Rat GLP-1 (total) U-PLEX Rat Glucagon U-PLEX Rat Insulin U-PLEX Rat Leptin U-PLEX Rat PYY (total)
Product Highlights		U-PLEX Platform Highlights
SDS		Biotin-conjugated Antibodies Safety Data Sheet Diluent 10, Diluent 11, Diluent 12, Diluent 13, Diluent 15, Diluent 16 and Diluent 17 MSD GOLD Read Buffer B U-PLEX Linker Set

Title	Journal	Year
Islet Autoantibody Standardization Program: interlaboratory comparison of insulin autoantibody assay performance in 2018 and 2020 workshops Ilaria Marzinotto, David L Pittman, Alistair J K Williams, Anna E Long, Peter Achenbach, Michael Schlosser, Beena Akolkar, William E Winter, Vito Lampasona; participating laboratories	Diabetologia	2023
Leptin levels are associated with multiple sclerosis risk Biström M, Hultdin J, Andersen O, Alonso-Magdalena L, Jons D, Gunnarsson M, Vrethem M, Sundström P	Multiple Sclerosis	2020
Genetic Deletion and Pharmacological Inhibition of Phosphodiesterase 10A Protects Mice From Diet-Induced Obesity and Insulin Resistance. Nawrocki AR, Rodriguez CG, Toolan DM, Price O, Henry M, Forrest G, Szeto D, Keohane CA, Pan Y, Smith KM, Raheem IT, Cox CD, Hwa J, Renger JJ, Smith SM.	Diabetes	2014
A multi-biomarker score measures rheumatoid arthritis disease activity in the BeSt study. Hirata S, Dirven L, Shen Y, Centola M, Cavet G, Lems WF, Tanaka Y, Huizinga TW, Allaart CF.	Rheumatology (Oxford)	2013
Beneficial effects of parenteral GLP-1 delivery by cell therapy in insulin-deficient streptozotocin diabetic mice. Vasu S, Moffett RC, McCluskey JT, Hamid MH, Irwin N, Flatt PR.	Gene Ther.	2013
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Kit Contents for Catalog No. K15309K-1

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Kit Contents for Catalog No. K15309K-4

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