The V-PLEX COVID-19 Coronavirus Panel 1 (ACE2) Kit is a multiplex neutralization assay that measures the antibodies capable of blocking the binding of angiotensin-converting enzyme 2 (ACE2) to the SARS-CoV-2 Spike and RBD antigens. The Panel serves as a high-throughput alternative to traditional neutralization assays. It includes nine (9) important antigens related to SARS-CoV-2, SARS-1, MERS, circulating Coronaviruses, and other respiratory diseases: Flu A/Hong Kong H3, HCoV-HKU1 Spike, HCoV-OC43 Spike, MERS-CoV Spike, SARS-CoV-1 Spike, SARS-CoV-2 N, SARS-CoV-2 S1 NTD, SARS-CoV-2 S1 RBD, and SARS-CoV-2 Spike.