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The V-PLEX SARS-CoV-2 Panel 27 (ACE2) Kit is a multiplex assay for antibodies that block the binding of ACE2 to Spike antigens from variants of SARS-CoV-2. It includes antigens from Beta, Delta, and several sublineages of Omicron, including BA.2, BA.2.12.1, BA.3, BA.4, BA.5, and two BA.2 Spike antigens with extra mutations predicted to further evade neutralization. Panel 27 includes: A (WT), (B.1.351), (B.1.617.2; AY.4) Alt Seq 2, (BA.2; BA.2.1; BA.2.2; BA.2.3; BA.2.5; BA.2.6; BA.2.7; BA.2.8; BA.2.10; BA.2.10.1; BA.2.12), (BA.2.12.1), (BA.2+L452M), (BA.2+L452R), (BA.3), (BA.4), and (BA.5).
Note: Alternative S-GENE mutations for Spike of B.1.617.2 are listed as "Alt Seq #."
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Specifications
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Kit Contents
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Documentation
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References
Analyte(s)
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SARS-CoV-2 Spike, SARS-CoV-2 Spike (B.1.351), SARS-CoV-2 Spike (B.1.617.2; AY.4), SARS-CoV-2 Spike (BA.2), SARS-CoV-2 Spike (BA.2.12.1), SARS-CoV-2 Spike (BA.2+L452M), SARS-CoV-2 Spike (BA.2+L452R), SARS-CoV-2 Spike (BA.3), SARS-CoV-2 Spike (BA.4), SARS-CoV-2 Spike (BA.5)
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Species
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Human
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Instrument(s)
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SECTOR Imager 2400
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MESO QuickPlex SQ 120MM
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MESO SECTOR S 600
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SECTOR Imager 6000
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MESO SECTOR S 600MM
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MESO QuickPlex SQ 120
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Plate Type
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96-well
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Sample Type
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Serum, Plasma
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Condition
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Multi-Component
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Schedule B Code
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3822.19.0000
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Product Description
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Storage
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Quantity per Kit
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ACE2 Calibration Reagent 2
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2-8 °C
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1 vial (65 μL)
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2-8 °C
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1 vial (5 plate size)
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SARS-CoV-2 Plate 27
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2-8 °C
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5 each (1 each)
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2-8 °C
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1 bottle (200 mL)
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RT
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1 bottle (90 mL)
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RT
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1 bottle (100 mL)
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MSD Blocker A
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RT
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1 bottle (250 mL)
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MSD Phosphate Buffer 5X
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RT
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1 bottle (50 mL)
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Product Description
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Storage
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Quantity per Kit
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ACE2 Calibration Reagent 2
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2-8 °C
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5 vial (65 μL)
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2-8 °C
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5 vial (5 plate size)
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SARS-CoV-2 Plate 27
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2-8 °C
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25 each (1 each)
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2-8 °C
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5 bottle (200 mL)
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RT
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5 bottle (90 mL)
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RT
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5 bottle (100 mL)
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MSD Blocker A
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RT
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5 bottle (250 mL)
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MSD Phosphate Buffer 5X
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RT
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5 bottle (50 mL)
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Product Inserts
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Handouts
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Technical Notes
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Certificate of analysis
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SDS
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Title
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Journal
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Year
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IgG Anti-Spike Antibodies and Surrogate Neutralizing Antibody Levels Decline Faster 3 to 10 Months After BNT162b2 Vaccination Than After SARS-CoV-2 Infection in Healthcare Workers
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Immune responses after omicron infection in triple-vaccinated health-care workers with and without previous SARS-CoV-2 infection
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Performance and validation of an adaptable multiplex assay for detection of serologic response to SARS-CoV-2 infection or vaccination
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Quantitative serology for SARS-CoV-2 using self-collected saliva and finger-stick blood
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Sensitive Serology Measurements in the Saliva of Individuals with COVID-19 Symptoms Using a Multiplexed Immunoassay
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