U-PLEX Metabolic Group 1 (mouse) 58-Plex

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The U-PLEX Metabolic Group 1 (mouse) 58-Plex is a panel of biomarkers that has been tested for multiplex compatibility and is fulfilled as a kit. It contains an extensive combination of assays for mouse metabolic biomarkers as well as many cytokines and chemokines (Table 1). The assays can be used for quantitative measurements in the sample types listed on the "Specifications" tab below, and offer detection limits (LLODs) in the sub- to low pg/mL range.

Table 1. List of analytes and typical detection limits

Analyte	LLOD - ULOD	units
BAFF	0.51 - 4,000	pg/mL
BCA-1/BLC	21 - 32,000	pg/mL
BDNF	0.72 - 2,000	pg/mL
CD40/TNFRSF5	2.6 - 8,000	pg/mL
C-Peptide	220 - 125,000	pg/mL
Eotaxin	4.6 - 15,000	pg/mL
EPO	4.5 - 12,500	pg/mL
FGF-21	2.8 - 8,230	pg/mL
Ghrelin (active)	13 - 7,160	pg/mL
Ghrelin (total)	1.7 - 2,710	pg/mL
GLP-1 (active)	0.14 - 57	pM
GLP-1 (inactive)	1.5 - 576	pM
GLP-1 (total)	0.59 - 576	pM
Glucagon	0.13 - 156	pM
GM-CSF	0.16 - 1,000	pg/mL
IFN-α	140 - 100,000	pg/mL
IFN-β	5.2 - 6,000	pg/mL
IFN-γ	0.16 - 2,900	pg/mL
IL-1β	3.1 - 13,000	pg/mL
IL-2	1.1 - 10,900	pg/mL
IL-4	0.56 - 10,000	pg/mL
IL-5	0.63 - 2,800	pg/mL
IL-6	4.8 - 16,000	pg/mL
IL-9	1.4 - 8,900	pg/mL
IL-10	3.8 - 22,800	pg/mL
IL-12/IL-23p40	1.4 - 20,400	pg/mL
IL-12p70	48 - 89,000	pg/mL
IL-13	2.7 - 22,800	pg/mL
IL-15	24 - 131,000	pg/mL

Analyte	LLOD - ULOD	units
IL-16	3.6 - 6,250	pg/mL
IL-17A	0.30 - 2,150	pg/mL
IL-17A/F	0.61 - 10,600	pg/mL
IL-17C	2.3 - 45,600	pg/mL
IL-17E/IL-25	1.6 - 18,900	pg/mL
IL-17F	24 - 52,600	pg/mL
IL-21	6.5 - 40,600	pg/mL
IL-22	1.2 - 1,850	pg/mL
IL-23	4.9 - 20,400	pg/mL
IL-27p28/IL-30	8.7 - 73,200	pg/mL
IL-31	45 - 66,200	pg/mL
IL-33	2.2 - 36,000	pg/mL
Insulin	3.0 - 5,500	μIU/mL
IP-10	0.51 - 4,900	pg/mL
KC/GRO	0.43 - 2,400	pg/mL
Leptin	11 - 50,000	pg/mL
MCP-1	1.4 - 1,400	pg/mL
MCP-5/CCL12	0.14 - 1,500	pg/mL
MDC	13 - 10,000	pg/mL
MIP-1α	0.21 - 2,100	pg/mL
MIP-1β	13 - 30,800	pg/mL
MIP-2	0.30 - 2,000	pg/mL
MIP-3α	0.10 - 2,500	pg/mL
MMP-9 (total)	49 - 80,000	pg/mL
PYY (total)	1.1 - 4,000	pg/mL
RANTES	0.72 - 2,000	pg/mL
TARC	0.32 - 1,200	pg/mL
TNF-α	1.3 - 6,200	pg/mL
VEGF-A	0.77 - 12,100	pg/mL

Specifications
Documentation
References

Application(s)		Metabolic
Analyte(s)		BAFF, BCA-1/BLC, BDNF, CD40/TNFRSF5, C-Peptide, Eotaxin, EPO, FGF-21, Ghrelin (active), Ghrelin (total), GLP-1 (active), GLP-1 (inactive), GLP-1 (total), Glucagon, GM-CSF, IFN-α, IFN-β, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, IL-17A/F, IL-17C, IL-17E/IL-25, IL-17F, IL-21, IL-22, IL-23, IL-27p28/IL-30, IL-31, IL-33, Insulin, IP-10, KC/GRO, Leptin, MCP-1, MCP-5/CCL12, MDC, MIP-1α, MIP-1β, MIP-2, MIP-3α, MMP-9 (total), PYY (total), RANTES, TARC, TNF-α, VEGF-A
Species		Mouse
Instrument(s)		SECTOR Imager 2400 , SECTOR Imager 6000 , MESO QuickPlex SQ 120 , MESO QuickPlex SQ 120MM , MESO SECTOR S 600 , MESO SECTOR S 600MM
U-PLEX Group Compatibility		Metabolic Group 1
Plate Type		96-well
Sample Type		Cell Culture Media, EDTA Plasma, P800 Plasma, Serum
Usage Statement		For Research Use Only. Not for use in diagnostic procedures.
Storage Condition		Multi-Component
Schedule B Code		3822.19.0000

Contact Information

Customer Service/Orders
1-240-314-2795

5:00 a.m. to 8:00 p.m.
US Eastern Time

Email

Scientific/Technical Support
1-240-314-2798

5:30 a.m. to 5:30 p.m.
US Eastern Time

Email

Instrument Support
1-301-947-2057

8:30 a.m. - 5:30 p.m.
US Eastern Time

Email

Company Headquarters
1-240-314-2600
1601 Research Blvd.
Rockville, Maryland 20850-3173
USA

Product Inserts		U-PLEX Metabolic Group 1 (mouse) Multiplex Insert
Datasheets		U-PLEX Mouse BAFF U-PLEX Mouse BCA-1/BLC U-PLEX Mouse BDNF U-PLEX Mouse CD40/TNFRSF5 U-PLEX Mouse C-Peptide U-PLEX Mouse Eotaxin U-PLEX Mouse EPO View More
Product Highlights		U-PLEX Platform Highlights
SDS		Biotin-conjugated Antibodies Safety Data Sheet Diluent 10, Diluent 11, Diluent 12, Diluent 13, Diluent 15, Diluent 16 and Diluent 17 MSD Calibrators and Controls MSD GOLD Read Buffer B U-PLEX Linker Set

Title	Journal	Year
Islet Autoantibody Standardization Program: interlaboratory comparison of insulin autoantibody assay performance in 2018 and 2020 workshops Ilaria Marzinotto, David L Pittman, Alistair J K Williams, Anna E Long, Peter Achenbach, Michael Schlosser, Beena Akolkar, William E Winter, Vito Lampasona; participating laboratories	Diabetologia	2023
Twenty-eight day repeated exposure of human 3D bronchial epithelial model to heated tobacco aerosols indicates decreased toxicological responses compared to cigarette smoke Fiona Chapman, Sarah Jean Pour, Roman Wieczorek, Edgar Trelles Sticken, Jessica Budde, Karin Röwer, Sandra Otte, Elizabeth Mason, Lukasz Czekala, Thomas Nahde, Grant O’Connell, Liam Simms and Matthew Stevenson	Frontiers in Toxicology	2023
A phase 1 study of prophylactic anakinra to mitigate ICANS in patients with large B-cell lymphoma Paolo Strati, Andrew Jallouk, Qing Deng, Xubin Li, Lei Feng, Ryan Sun, Sherry Adkins, Swapna Johncy, Taylor Cain, Raphael E. Steiner, Sairah Ahmed, Dai Chihara, Luis E. Fayad, Swaminathan P. Iyer, Sandra Horowitz, Loretta J. Nastoupil, Ranjit Nair, Ahmed Hassan, Taher E. Daoud, Misha Hawkins, Maria A. Rodriguez, Elizabeth J. Shpall, Jeremy L. Ramdial, Partow Kebriaei, David S. Hong, Jason R. Westin, Sattva S. Neelapu, Michael R. Green	Blood Advances	2023
Viral Antigen and Inflammatory Biomarkers in Cerebrospinal Fluid in Patients With COVID-19 Infection and Neurologic Symptoms Compared With Control Participants Without Infection or Neurologic Symptoms Arvid Edén, Anna Grahn, Daniel Bremell, Anahit Aghvanyan, Pradeepthi Bathala, Dietmar Fuchs, Johanna Gostner, Lars Hagberg, Nelly Kanberg, Sunsanee Kanjananimmanont, Magnus Lindh, Salvia Misaghian, Staffan Nilsson, Michael Schöll, George Sigal, Erika Stentoft, Marie Studahl, Aylin Yilmaz, Mingyue Wang, Martin Stengelin, Henrik Zetterberg, Magnus Gisslén	JAMA Network Open	2022
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations Bing Sun, Norina Tang, Michael J. Peluso, Nikita S. Iyer, Leonel Torres, Joanna L. Donatelli, Sadie E. Munter, Christopher C. Nixon, Rachel L. Rutishauser, Isabel Rodriguez-Barraquer, Bryan Greenhouse, John D. Kelly, Jeffrey N. Martin, Steven G. Deeks, Timothy J. Henrich, and Lynn Pulliam	Cells	2021
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