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U-PLEX Combos offer popular panels of biomarkers that have been grouped together for convenient ordering. They have been tested for multiplex compatibility and are fulfilled as a kit. The U-PLEX Effector Cell Checkpoint Combo 1 (human) combines 10 analytes (Table 1) of immune checkpoints on effector cells. The assays can be used for quantitative measurements of the sample type(s) listed in the "Specifications" tab below, and offer detection limits (LLODs) in the sub- to low pg/mL range.
| Analyte | LLOD - ULOD | Unit |
| CD27 | 0.41 - 3,400 | pg/mL |
| CD28 | 14 - 144,000 | pg/mL |
| CD40L (soluble) | 0.23 - 1,800 | pg/mL |
| CTLA-4 | 0.12 - 1,500 | pg/mL |
| GITR/TNFRSF18 | 0.18 - 1,300 | pg/mL |
| HAVCR2/TIM-3 | 2.1 - 9,500 | pg/mL |
| LAG3 | 6.8 - 36,000 | pg/mL |
| OX40 | 0.26 - 1,800 | pg/mL |
| PD1 (epitope 1) | 0.25 - 2,200 | pg/mL |
| TIGIT | 0.36 - 3,500 | pg/mL |
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Specifications
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Kit Contents
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Documentation
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References
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Analyte(s)
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CD27, CD28, CD40L (soluble), CTLA-4, GITR/TNFRSF18, HAVCR2/TIM-3, LAG3, OX40/TNFRSF4, PD1 (epitope 1), TIGIT
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Species
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Human
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Instrument(s)
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SECTOR Imager 2400
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MESO QuickPlex SQ 120MM
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MESO SECTOR S 600
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SECTOR Imager 6000
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MESO SECTOR S 600MM
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MESO QuickPlex SQ 120
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U-PLEX Group Compatibility
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Immuno-Oncology Group 1
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Plate Type
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96-well
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Sample Type
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Plasma, Serum
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Schedule B Code
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3822.19.0000
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Product Description
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Storage
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Quantity per Kit
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Effector Cell Checkpt Combo 1 (hu),Box 1 of 2 (1 PL)
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Multi-Component
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1 each
(1 each)
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Effector Cell Checkpt Combo 1 (hu),Box 2 of 2 (1 PL)
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Multi-Component
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1 each
(1 each)
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Product Description
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Storage
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Quantity per Kit
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Effector Cell Checkpoint Combo 1 (hu),Box 1 of 2 (5 PL)
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Multi-Component
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1 each
(5 each)
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Effector Cell Checkpt Combo 1 (hu),Box 2 of 2 (5 PL)
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Multi-Component
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1 each
(5 each)
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Product Description
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Storage
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Quantity per Kit
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Effector Cell Checkpt Combo 1 (hu),Box 1 of 2(25 PL)
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Multi-Component
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1 each
(25 each)
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Effector Cell Checkpt Combo 1 (hu),Box 2 of 2(25 PL)
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Multi-Component
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1 each
(25 each)
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Product Inserts
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Datasheets
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View More
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Product Highlights
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SDS
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Title
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Journal
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Year
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Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial
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Order Details
Catalog No
Size
Price in USD
Qty
Customer Service/Orders
Scientific/Technical Support
Instrument Support
Company Headquarters