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The V-PLEX SARS-CoV-2 Panel 25 (ACE2) Kit is a multiplex assay for antibodies that block the binding of ACE2 to Spike antigens from variants of SARS-CoV-2. It includes antigens from Alpha, Beta, Delta and Omicron, including two BA.1 Spike antigens with extra mutations predicted to further evade neutralization. Panel 25 includes: A (WT), (B.1.1.7), (B.1.1.529; BA.1; B.1.15), (B.1.351), (B.1.617.2; AY.4) Alt Seq 2, (B.1.640.2), (BA.1+L452R), (BA.1+R346K; BA.1.1; BA.1.1.15), (BA.2; BA.2.1; BA.2.2; BA.2.3; BA.2.5; BA.2.6; BA.2.7; BA.2.8; BA.2.10; BA.2.10.1; BA.2.12), and (BA.3).
Note: Alternative S-GENE mutations for Spike of B.1.617.2 are listed as "Alt Seq #."
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Specifications
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Kit Contents
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Documentation
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References
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Analyte(s)
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SARS-CoV-2 Spike, SARS-CoV-2 Spike (B.1.1.7), SARS-CoV-2 Spike (B.1.1.529; BA.1), SARS-CoV-2 Spike (B.1.351), SARS-CoV-2 Spike (B.1.617.2; AY.4), SARS-CoV-2 Spike (B.1.640.2), SARS-CoV-2 Spike (BA.1+L452R), SARS-CoV-2 Spike (BA.1+R346K), SARS-CoV-2 Spike (BA.2), SARS-CoV-2 Spike (BA.3)
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Species
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Human
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Instrument(s)
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SECTOR Imager 2400
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MESO QuickPlex SQ 120MM
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MESO SECTOR S 600
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SECTOR Imager 6000
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MESO SECTOR S 600MM
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MESO QuickPlex SQ 120
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Plate Type
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96-well
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Sample Type
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Serum, Plasma
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Condition
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Multi-Component
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Schedule B Code
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3822.19.0000
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Product Description
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Storage
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Quantity per Kit
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ACE2 Calibration Reagent 2
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2-8 °C
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1 vial
(65 μL)
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2-8 °C
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1 vial
(5 plate size)
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SARS-CoV-2 Plate 25
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2-8 °C
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5 each
(1 each)
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2-8 °C
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1 bottle
(200 mL)
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RT
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1 bottle
(90 mL)
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RT
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1 bottle
(100 mL)
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MSD Blocker A
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RT
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1 bottle
(250 mL)
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MSD Phosphate Buffer
5X
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RT
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1 bottle
(50 mL)
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Product Description
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Storage
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Quantity per Kit
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ACE2 Calibration Reagent 2
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2-8 °C
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5 vial
(65 μL)
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2-8 °C
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5 vial
(5 plate size)
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SARS-CoV-2 Plate 25
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2-8 °C
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25 each
(1 each)
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2-8 °C
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5 bottle
(200 mL)
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RT
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5 bottle
(90 mL)
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RT
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5 bottle
(100 mL)
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MSD Blocker A
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RT
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5 bottle
(250 mL)
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MSD Phosphate Buffer
5X
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RT
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5 bottle
(50 mL)
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Product Inserts
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Handouts
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Technical Notes
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Certificate of analysis
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SDS
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Title
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Journal
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Year
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IgG Anti-Spike Antibodies and Surrogate Neutralizing Antibody Levels Decline Faster 3 to 10 Months After BNT162b2 Vaccination Than After SARS-CoV-2 Infection in Healthcare Workers
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Immune responses after omicron infection in triple-vaccinated health-care workers with and without previous SARS-CoV-2 infection
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Performance and validation of an adaptable multiplex assay for detection of serologic response to SARS-CoV-2 infection or vaccination
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Sensitive Serology Measurements in the Saliva of Individuals with COVID-19 Symptoms Using a Multiplexed Immunoassay
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Quantitative serology for SARS-CoV-2 using self-collected saliva and finger-stick blood
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