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The
V-PLEX platform offers analytically validated singleplex and multiplex assay kits. Developed under rigorous design control, V-PLEX kits provide accurate and reproducible results with consistency from lot to lot. The V-PLEX Plus Mouse Cytokine 19-Plex Kit includes 19 biomarkers associated with the inflammatory response and immune system regulation (Table 1). The assays can be used for quantitative measurements in the sample types listed in the “Specifications” tab below and offer detection limits (LLODs and LLOQs) in the sub- to low pg/mL range.
V-PLEX Plus kits include controls, wash buffer, and plate seals.
| Analyte | LLOD | LLOQ | ULOQ | Dynamic Range | Unit | | IFN-γ | 0.04 | 0.39 | 570 | 0.04 - 570 | pg/mL |
| IL-1β | 0.11 | 0.72 | 1,030 | 0.11 - 1,030 | pg/mL |
| IL-2 | 0.22 | 1.03 | 1,570 | 0.22 - 1,570 | pg/mL |
| IL-4 | 0.11 | 0.818 | 1,060 | 0.11 - 1,060 | pg/mL |
| IL-5 | 0.06 | 0.302 | 590 | 0.06 - 590 | pg/mL |
| IL-6 | 0.61 | 7.61 | 3,140 | 0.61 - 3,140 | pg/mL |
| IL-9 | 3.84 | 21.9 | 2,600 | 3.84 - 2,600 | pg/mL |
| IL-10 | 0.94 | 7.26 | 2,030 | 0.94 - 2,030 | pg/mL |
| IL-12p70 | 9.95 | 179 | 20,600 | 9.95 - 20,600 | pg/mL |
| IL-15 | 16 | 43.2 | 26,000 | 16.0 - 26,000 | pg/mL |
| IL-17A/F | 0.231 | 1.39 | 1,620 | 0.231 - 1,620 | pg/mL |
| IL-27p28/IL-30 | 1.39 | 5.91 | 6,500 | 1.39 - 6,500 | pg/mL |
| IL-33 | 0.364 | 1.85 | 1,950 | 0.364 - 1,950 | pg/mL |
| IP-10 | 0.328 | 2.15 | 650 | 0.328 - 650 | pg/mL |
| KC/GRO | 0.24 | 3.29 | 1,230 | 0.24 - 1,230 | pg/mL |
| MCP-1 | 0.672 | 4.42 | 325 | 0.672 - 325 | pg/mL |
| MIP-1α | 0.081 | 0.38 | 390 | 0.081 - 390 | pg/mL |
| MIP-2 | 0.053 | 0.58 | 423 | 0.053 - 423 | pg/mL |
| TNF-α | 0.13 | 0.98 | 403 | 0.13 - 403 | pg/mL |
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Specifications
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Kit Contents
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Documentation
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References
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Application(s)
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Cytokines & Chemokines
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Immunology/Inflammation
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Analyte(s)
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IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p70, IL-15, IL-17A/F, IL-27p28/IL-30, IL-33, IP-10, KC/GRO, MCP-1, MIP-1α, MIP-2, TNF-α
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Species
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Mouse
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Instrument(s)
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SECTOR Imager 2400
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MESO SECTOR S 600MM
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SECTOR Imager 6000
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MESO QuickPlex SQ 120MM
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MESO QuickPlex SQ 120
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MESO SECTOR S 600
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Plate Type
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96-well
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Sample Type
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Serum, Plasma, Cell Culture Supernatant, Urine
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Schedule B Code
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3822.19.0000
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Product Description
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Storage
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Quantity per Kit
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Multi-Component
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1 each
(1 plate size)
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Multi-Component
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1 each
(1 plate size)
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Product Description
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Storage
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Quantity per Kit
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Multi-Component
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1 each
(5 plate size)
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Multi-Component
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1 each
(5 plate size)
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Product Description
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Storage
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Quantity per Kit
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Multi-Component
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1 each
(25 plate size)
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Multi-Component
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1 each
(25 plate size)
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Title
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Journal
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Year
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Twenty-eight day repeated exposure of human 3D bronchial epithelial model to heated tobacco aerosols indicates decreased toxicological responses compared to cigarette smoke
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A phase 1 study of prophylactic anakinra to mitigate ICANS in patients with large B-cell lymphoma
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Viral Antigen and Inflammatory Biomarkers in Cerebrospinal Fluid in Patients With COVID-19 Infection and Neurologic Symptoms Compared With Control Participants Without Infection or Neurologic Symptoms
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Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations
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Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection
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