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U-PLEX NHP IL-23 Assay

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The U-PLEX platform offers validated components that can be combined to create high quality assays quickly and easily. The U-PLEX Non-human primate IL-23 Assay has the essential components for an assay that measures IL-23 in a single-analyte format. For information on multiplexing IL-23 with other analytes, please see U-PLEX Custom Biomarker Group 1 (NHP) Assays.

Related Key Terms:
CLMF2, NKSF2, p19/IL-12p40 heterodimer, IL-12 cytokine family, interleukin, immunity, inflammation, Th17, autoimmunity, arthritis, diabetes, Crohn's disease, multiple sclerosis, psoriasis

Specifications
Kit Contents
Documentation
References

Application(s)		Cytokines & Chemokines , Immunology/Inflammation
Analyte(s)		IL-23
Species		Non-human primate
Instrument(s)		SECTOR Imager 2400 , MESO SECTOR S 600MM , SECTOR Imager 6000 , MESO QuickPlex SQ 120MM , MESO QuickPlex SQ 120 , MESO SECTOR S 600
U-PLEX Group Compatibility		Biomarker Group 1
Plate Type		96-well
Capture Antibody		Mouse Monoclonal
Detection Antibody		Mouse Monoclonal
LLOD (Sensitivity)		1.4 pg/mL
Dynamic Range		1.4 – 21,600 pg/mL
Sample Type		Serum, Plasma, Cell Culture Supernatant
Recombinant standards		Expressed in insect cells
Usage Statement		For Research Use Only. Not for use in diagnostic procedures.
Storage Statement(s)		Please refer to the product insert for the storage conditions of individual kit components.
Storage Condition		Multi-Component
Gene ID(s)		712627, 694747
UniProt ID(s)		F7HQI5, P48095
Schedule B Code		3822.19.0000

Product Description	Storage	Quantity per Kit
U-PLEX Human IL-23 Antibody Set (1 Plate Size)	2-8 °C	1 each (1 plate size)

Calibrator 6	2-8 °C	1 vial (1 vial)

MSD GOLD 96 Small Spot SA Plate Pack, SECTOR Plate	2-8 °C	1 each (1 plate)

Diluent 100	2-8 °C	1 bottle (50 mL)

Diluent 3	≤-10 °C	1 bottle (8 mL)

Diluent 57	≤-10 °C	1 bottle (10 mL)

MSD GOLD Read Buffer B	RT	1 bottle (18 mL)

Product Description	Storage	Quantity per Kit
U-PLEX Human IL-23 Antibody Set (5 Plate Size)	2-8 °C	1 each (5 plate size)

Calibrator 6	2-8 °C	5 vial (1 vial)

MSD GOLD 96 Small Spot SA Plate Pack, SECTOR Plate	2-8 °C	5 each (1 plate)

Diluent 100	2-8 °C	1 bottle (50 mL)

Diluent 3	≤-10 °C	1 bottle (40 mL)

Diluent 57	≤-10 °C	1 bottle (50 mL)

MSD GOLD Read Buffer B	RT	1 bottle (90 mL)

Product Description	Storage	Quantity per Kit
U-PLEX Human IL-23 Antibody Set (5 Plate Size)	2-8 °C	5 each (5 plate size)

Calibrator 6	2-8 °C	25 vial (1 vial)

MSD GOLD 96 Small Spot SA Plate Pack, SECTOR Plate	2-8 °C	25 each (1 plate)

Diluent 100	2-8 °C	5 bottle (50 mL)

Diluent 3	≤-10 °C	5 bottle (40 mL)

Diluent 57	≤-10 °C	5 bottle (50 mL)

MSD GOLD Read Buffer B	RT	5 bottle (90 mL)

Order Details

Catalog No

Size

Price in USD

Qty

K156WGK-1

1 plate

$485.00

Usually ships in 1-3 days

K156WGK-2

5 plates

$1,940.00

Usually ships in 1-3 days

K156WGK-4

25 plates

$8,489.00

Usually ships in 1-3 days

Contact Information

Customer Service/Orders
1-240-314-2795

5:00 a.m. to 8:00 p.m.
US Eastern Time

Email

Scientific/Technical Support
1-240-314-2798

5:30 a.m. to 5:30 p.m.
US Eastern Time

Email

Instrument Support
1-301-947-2057

8:30 a.m. - 5:30 p.m.
US Eastern Time

Email

Company Headquarters
1-240-314-2600
1601 Research Blvd.
Rockville, Maryland 20850-3173
USA

Product Inserts		U-PLEX Biomarker Group 1 (NHP) Singleplex Insert
Datasheets		U-PLEX NHP IL-23
Product Highlights		U-PLEX Platform Highlights
SDS		Biotin-conjugated Antibodies Safety Data Sheet Diluent 2, Diluent 3, Diluent 5, Diluent 7 and Diluent 8 Diluent 50, Diluent 56, Diluent 61, Diluent 100, and Diluent 101 Diluent 57, Diluent 58, and Diluent 59 MSD Calibrators and Controls MSD GOLD Read Buffer B

Title	Journal	Year
Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease-associated psychological morbidity Bain KA, McDonald E, Moffat F, Tutino M, Castelino M, Barton A, Cavanagh J, Ijaz UZ, Siebert S, McInnes IB, Astrand A, Holmes S, Milling SWF	British Journal of Dermatology	2019
Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab. Luo, J., Wu, S.J., Lacy, E.R., Orlovsky, Y., Baker, A., Teplyakov, A., Obmolova, G., Heavner, G.A., Richter, H.T., Benson, J.	J Mol Biol.	2010
Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations. Gourh, P., Arnett, F.C., Assassi, S., Tan, F.K., Huang, M., Diekman, L., Mayes, M.D., Reveille, J.D., Agarwal, S.K.	Arthritis Res Ther.	2009

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U-PLEX NHP IL-23 Assay

Kit Contents for Catalog No. K156WGK-1

Kit Contents for Catalog No. K156WGK-2

Kit Contents for Catalog No. K156WGK-4

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