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The
U-PLEX platform offers validated components that can be combined to create high quality assays quickly and easily. The U-PLEX Human GLP-1 (total) 384-well Assay has the essential components for an assay that measures GLP-1 (total) in a single-analyte format on 384-well plates. For information on multiplexing GLP-1 (total) with other analytes, please see
U-PLEX Custom Metabolic Group 1 (human) Assays.
Related Key Terms: Glucagon-Like Peptide-1, GLP-1, metabolic diseases, metabolism, proglucagon, insulin, diabetes
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Specifications
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Kit Contents
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Product Details
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Documentation
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References
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Application(s)
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Metabolic
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Analyte(s)
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GLP-1 (total)
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Species
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Human
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Instrument(s)
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MESO SECTOR S 600
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SECTOR Imager 6000
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MESO SECTOR S 600MM
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U-PLEX Group Compatibility
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Metabolic Group 1
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Plate Type
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384-well
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Capture Antibody
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Mouse monoclonal
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Detection Antibody
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Mouse monoclonal
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LLOD (Sensitivity)
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0.59 pM
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Dynamic Range
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0.59 - 576 pM
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Sample Type
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Serum, EDTA Plasma, P800 Plasma
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Gene ID(s)
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2641
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UniProt ID(s)
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P01275
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Schedule B Code
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3822.19.0000
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Product Description
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Storage
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Quantity per Kit
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2-8 °C
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1 each
(5 plate size)
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2-8 °C
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5 vial
(1 vial)
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2-8 °C
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5 each
(1 plate)
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2-8 °C
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2 bottle
(50 mL)
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≤-10 °C
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2 bottle
(50 mL)
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≤-10 °C
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2 bottle
(50 mL)
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RT
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1 bottle
(90 mL)
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Aprotinin
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2-8 °C
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2 vial
(250 μL)
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Product Description
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Storage
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Quantity per Kit
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2-8 °C
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5 each
(5 plate size)
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2-8 °C
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25 vial
(1 vial)
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2-8 °C
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25 each
(1 plate)
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2-8 °C
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10 bottle
(50 mL)
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≤-10 °C
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10 bottle
(50 mL)
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≤-10 °C
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10 bottle
(50 mL)
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RT
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5 bottle
(90 mL)
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Aprotinin
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2-8 °C
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10 vial
(250 μL)
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Notes: - The U-PLEX Human GLP-1 (total) Assay has been designed to eliminate a bias towards the active fragment of GLP-1 that was observed in the previous MSD Total GLP-1 (ver. 2) assay. The U-PLEX Human GLP-1 (total) Assay detects both active and inactive fragments of GLP-1 equivalently and enables improved quantitation of total GLP-1 in samples. Because of these changes, concentrations of samples will not correlate between the U-PLEX Human GLP-1 (total) Assay and the previous MSD Total GLP-1 (ver. 2) assay. Please contact MSD Scientific Support for further information.
- GLP-1 (7-36; active) and GLP-1 (9-36; inactive) cross-react with the GLP-1 (total) assay as expected. We do not recommend multiplexing the GLP (total) assay with the GLP (inactive) or GLP (active) assays on the same plate.
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Product Inserts
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Datasheets
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Product Highlights
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SDS
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Title
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Journal
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Year
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Beneficial effects of parenteral GLP-1 delivery by cell therapy in insulin-deficient streptozotocin diabetic mice.
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Concomitant use of miglitol and mitiglinide as initial combination therapy in type 2 diabetes mellitus.
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Consumption of buckwheat modulates the post-prandial response of selected gastrointestinal satiety hormones in individuals with type 2 diabetes mellitus.
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Diacylglycerol Acyltransferase-1 (DGAT1) inhibition perturbs postprandial gut hormone release.
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Effect of orally administered L. fermentum NCIMB 5221 on markers of metabolic syndrome: an in vivo analysis using ZDF rats
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