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S-PLEX is MSD’s ultra-sensitive assay platform. It can dramatically improve the sensitivity of immunoassays, reducing the lower limit of detection (LLOD) by 10- to 1000-fold over other assay methods. The S-PLEX SARS-CoV-2 Spike Assay has the essential components for an ultra-sensitive assay that measures SARS-CoV-2 Spike in a single-analyte format. For detailed instructions on running the SARS-CoV-2 Spike assay, please see the product insert in the "Documentation" tab below.
Related Key Terms: S1, S1-S2, COVID-19, S1-RBD, coronavirus
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Specifications
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Kit Contents
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Documentation
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References
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Analyte(s)
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SARS-CoV-2 Spike
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Species
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Human
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Instrument(s)
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SECTOR Imager 2400
,
MESO QuickPlex SQ 120MM
,
MESO SECTOR S 600
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SECTOR Imager 6000
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MESO SECTOR S 600MM
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MESO QuickPlex SQ 120
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Plate Type
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96-well
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Capture Antibody
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Mouse Monoclonal
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Detection Antibody
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Mouse Monoclonal
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LLOD (Sensitivity)
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95 fg/mL
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Dynamic Range
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95 - 376,000 fg/mL
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Sample Type
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Upper Respiratory Sample, Saliva, Serum, EDTA Plasma
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Recombinant standards
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Expressed in Human cell line
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Condition
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Multi-Component
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Schedule B Code
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3822.19.0000
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Product Description
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Storage
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Quantity per Kit
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S-PLEX SARS-CoV-2 Spike Antibody Set
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2-8 °C
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1 each
(1 plate size)
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SARS-CoV-2 Spike Calibrator
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≤-70 °C
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1 vial
(1 vial)
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S-PLEX Coating Reagent C1
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≤-70 °C
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1 vial
(300 μL)
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S-PLEX Detect D2
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≤-70 °C
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1 each
(50 μL)
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S-PLEX Detect D1
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≤-70 °C
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1 each
(1.7 mL)
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S-PLEX 96-Well SECTOR Plate
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2-8 °C
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1 each
(1 plate)
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2-8 °C
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1 bottle
(50 mL)
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2-8 °C
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1 bottle
(8 mL)
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≤-10 °C
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1 bottle
(8 mL)
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RT
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1 bottle
(18 mL)
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S-PLEX Enhance E1
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≤-10 °C
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1 each
(1.7 mL)
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S-PLEX Enhance E2
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≤-10 °C
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1 vial
(1.7 mL)
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S-PLEX Enhance E3
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≤-70 °C
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1 each
(50 μL)
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≤-10 °C
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1 vial
(500 μL)
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Product Description
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Storage
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Quantity per Kit
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S-PLEX SARS-CoV-2 Spike Antibody Set
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2-8 °C
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1 each
(5 plate size)
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SARS-CoV-2 Spike Calibrator
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≤-70 °C
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5 vial
(1 vial)
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S-PLEX Coating Reagent C1
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≤-70 °C
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1 vial
(300 μL)
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S-PLEX Detect D2
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≤-70 °C
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5 each
(50 μL)
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S-PLEX Detect D1
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≤-70 °C
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5 each
(1.7 mL)
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S-PLEX 96-Well SECTOR Plate
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2-8 °C
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5 each
(1 plate)
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2-8 °C
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1 bottle
(50 mL)
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2-8 °C
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1 bottle
(40 mL)
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≤-10 °C
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1 bottle
(40 mL)
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RT
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1 bottle
(90 mL)
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S-PLEX Enhance E1
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≤-10 °C
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5 each
(1.7 mL)
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S-PLEX Enhance E2
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≤-10 °C
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5 vial
(1.7 mL)
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S-PLEX Enhance E3
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≤-70 °C
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5 each
(50 μL)
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≤-10 °C
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1 vial
(500 μL)
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Product Description
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Storage
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Quantity per Kit
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S-PLEX SARS-CoV-2 Spike Antibody Set
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2-8 °C
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5 each
(5 plate size)
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SARS-CoV-2 Spike Calibrator
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≤-70 °C
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25 vial
(1 vial)
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S-PLEX Coating Reagent C1
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≤-70 °C
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5 vial
(300 μL)
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S-PLEX Detect D2
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≤-70 °C
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25 each
(50 μL)
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S-PLEX Detect D1
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≤-70 °C
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25 each
(1.7 mL)
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S-PLEX 96-Well SECTOR Plate
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2-8 °C
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25 each
(1 plate)
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2-8 °C
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5 bottle
(50 mL)
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2-8 °C
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5 bottle
(40 mL)
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≤-10 °C
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5 bottle
(40 mL)
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RT
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5 bottle
(90 mL)
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S-PLEX Enhance E1
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≤-10 °C
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25 each
(1.7 mL)
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S-PLEX Enhance E2
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≤-10 °C
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25 vial
(1.7 mL)
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S-PLEX Enhance E3
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≤-70 °C
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25 each
(50 μL)
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≤-10 °C
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5 vial
(500 μL)
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Product Inserts
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Certificate of analysis
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SDS
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Title
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Journal
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Year
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IgG Anti-Spike Antibodies and Surrogate Neutralizing Antibody Levels Decline Faster 3 to 10 Months After BNT162b2 Vaccination Than After SARS-CoV-2 Infection in Healthcare Workers
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Immune responses after omicron infection in triple-vaccinated health-care workers with and without previous SARS-CoV-2 infection
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Performance and validation of an adaptable multiplex assay for detection of serologic response to SARS-CoV-2 infection or vaccination
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Sensitive Serology Measurements in the Saliva of Individuals with COVID-19 Symptoms Using a Multiplexed Immunoassay
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Quantitative serology for SARS-CoV-2 using self-collected saliva and finger-stick blood
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