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S-PLEX is MSD’s ultrasensitive assay platform. It can dramatically improve the sensitivity of immunoassays, reducing the lower limit of detection (LLOD) by 10- to 1000-fold over other assay methods. The S-PLEX Proinflammatory Panel 1 (human) Kit includes nine biomarkers that are associated with the inflammation response and immune system regulation, as well as numerous other biological processes (Table 1). The assays can be used for quantitative measurements in the sample types listed in the “Specifications” tab below and offer detection limits in the fg/mL range.
| Analyte |
Median LLOD |
Dynamic Range |
Unit |
| IFN-γ |
9.0 |
9.0 - 21,000 |
fg/mL |
| IL-1β |
71 |
71 - 110,000 |
fg/mL |
| IL-2 |
12 |
12 - 53,000 |
fg/mL |
| IL-4 |
8.0 |
8.0 - 36,000 |
fg/mL |
| IL-6 |
11 |
11 - 36,000 |
fg/mL |
| IL-10 |
19 |
19 - 120,000 |
fg/mL |
| IL-12p70 |
43 |
43 - 320,000 |
fg/mL |
| IL-17A |
44 |
44 - 170,000 |
fg/mL |
| TNF-α |
11 |
11 - 35,000 |
fg/mL |
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Specifications
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Kit Contents
-
Documentation
-
References
|
Application(s)
|
|
Cytokines & Chemokines
,
Immunology/Inflammation
|
|
|
Analyte(s)
|
|
IFN-γ, IL-1β, IL-2, IL-4, IL-6, IL-10, IL-12p70, IL-17A, TNF-α
|
|
|
Species
|
|
Human
|
|
|
Instrument(s)
|
|
SECTOR Imager 2400
,
MESO QuickPlex SQ 120MM
,
MESO SECTOR S 600
,
SECTOR Imager 6000
,
MESO SECTOR S 600MM
,
MESO QuickPlex SQ 120
|
|
|
Plate Type
|
|
96-well
|
|
|
Sample Type
|
|
Serum, Plasma, Cell Culture Supernatant, CSF, Urine
|
|
|
Usage Statement
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
|
|
Storage Condition
|
|
Multi-Component
|
|
|
Schedule B Code
|
|
3822.19.0000
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
Diluent 58
|
≤-10 °C
|
1 bottle
(10 mL)
|
|
|
|
S-PLEX Proinflammatory Panel 1 (human) Calibrator Blend
|
2-8 °C
|
1 vial
(1 vial)
|
|
|
|
S-PLEX Proinflammatory Panel 1 (human) Coating Solution
|
≤-70 °C
|
1 vial
(1 vial)
|
|
|
|
S-PLEX Detect D2
|
≤-70 °C
|
1 each
(50 μL)
|
|
|
|
S-PLEX Detect D1
|
≤-70 °C
|
1 each
(1.7 mL)
|
|
|
|
TURBO-BOOST Human IL-6 Antibody
|
2-8 °C
|
1 vial
(1 plate size)
|
|
|
|
TURBO-BOOST Human IL-10 Antibody
|
2-8 °C
|
1 vial
(1 plate size)
|
|
|
|
TURBO-BOOST Human IL-12p70 Antibody
|
2-8 °C
|
1 vial
(1 plate size)
|
|
|
|
TURBO-BOOST Human IL-4 Antibody
|
2-8 °C
|
1 vial
(1 plate size)
|
|
|
|
TURBO-BOOST Human IL-2 Antibody
|
2-8 °C
|
1 vial
(1 plate size)
|
|
|
|
TURBO-BOOST Human TNF-α Antibody
|
2-8 °C
|
1 vial
(1 plate size)
|
|
|
|
TURBO-BOOST Human IL-1β Antibody
|
2-8 °C
|
1 vial
(1 plate size)
|
|
|
|
TURBO-BOOST Human IFN-γ Antibody
|
2-8 °C
|
1 vial
(1 plate size)
|
|
|
|
TURBO-BOOST Human IL-17A Antibody
|
2-8 °C
|
1 vial
(1 plate size)
|
|
|
|
S-PLEX Multiplex, 96-Well SECTOR Plate
|
2-8 °C
|
1 each
(1 each)
|
|
|
|
|
2-8 °C
|
1 bottle
(50 mL)
|
|
|
|
|
2-8 °C
|
1 bottle
(8 mL)
|
|
|
|
|
RT
|
1 bottle
(18 mL)
|
|
|
|
S-PLEX Enhance E1
|
≤-10 °C
|
1 each
(1.7 mL)
|
|
|
|
S-PLEX Enhance E2
|
≤-10 °C
|
1 vial
(1.7 mL)
|
|
|
|
S-PLEX Enhance E3
|
≤-70 °C
|
1 each
(50 μL)
|
|
|
|
|
≤-10 °C
|
1 vial
(500 μL)
|
|
|
|
Blocker S2
|
≤-10 °C
|
1 vial
(500 μL)
|
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
Diluent 58
|
≤-10 °C
|
1 bottle
(50 mL)
|
|
|
|
S-PLEX Proinflammatory Panel 1 (human) Calibrator Blend
|
2-8 °C
|
5 vial
(1 vial)
|
|
|
|
S-PLEX Proinflammatory Panel 1 (human) Coating Solution
|
≤-70 °C
|
5 vial
(1 vial)
|
|
|
|
S-PLEX Detect D2
|
≤-70 °C
|
5 each
(50 μL)
|
|
|
|
S-PLEX Detect D1
|
≤-70 °C
|
5 each
(1.7 mL)
|
|
|
|
TURBO-BOOST Human IL-6 Antibody
|
2-8 °C
|
1 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IL-10 Antibody
|
2-8 °C
|
1 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IL-12p70 Antibody
|
2-8 °C
|
1 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IL-4 Antibody
|
2-8 °C
|
1 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IL-2 Antibody
|
2-8 °C
|
1 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human TNF-α Antibody
|
2-8 °C
|
1 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IL-1β Antibody
|
2-8 °C
|
1 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IFN-γ Antibody
|
2-8 °C
|
1 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IL-17A Antibody
|
2-8 °C
|
1 vial
(5 plate size)
|
|
|
|
S-PLEX Multiplex, 96-Well SECTOR Plate
|
2-8 °C
|
5 each
(1 each)
|
|
|
|
|
2-8 °C
|
1 bottle
(50 mL)
|
|
|
|
|
2-8 °C
|
1 bottle
(40 mL)
|
|
|
|
|
RT
|
1 bottle
(90 mL)
|
|
|
|
S-PLEX Enhance E1
|
≤-10 °C
|
5 each
(1.7 mL)
|
|
|
|
S-PLEX Enhance E2
|
≤-10 °C
|
5 vial
(1.7 mL)
|
|
|
|
S-PLEX Enhance E3
|
≤-70 °C
|
5 each
(50 μL)
|
|
|
|
|
≤-10 °C
|
1 vial
(500 μL)
|
|
|
|
Blocker S2
|
≤-10 °C
|
1 vial
(500 μL)
|
|
|
|
Product Description
|
Storage
|
Quantity per Kit
|
|
Diluent 58
|
≤-10 °C
|
5 bottle
(50 mL)
|
|
|
|
S-PLEX Proinflammatory Panel 1 (human) Calibrator Blend
|
2-8 °C
|
25 vial
(1 vial)
|
|
|
|
S-PLEX Proinflammatory Panel 1 (human) Coating Solution
|
≤-70 °C
|
25 vial
(1 vial)
|
|
|
|
S-PLEX Detect D2
|
≤-70 °C
|
25 each
(50 μL)
|
|
|
|
S-PLEX Detect D1
|
≤-70 °C
|
25 each
(1.7 mL)
|
|
|
|
TURBO-BOOST Human IL-6 Antibody
|
2-8 °C
|
5 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IL-10 Antibody
|
2-8 °C
|
5 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IL-12p70 Antibody
|
2-8 °C
|
5 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IL-4 Antibody
|
2-8 °C
|
5 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IL-2 Antibody
|
2-8 °C
|
5 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human TNF-α Antibody
|
2-8 °C
|
5 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IL-1β Antibody
|
2-8 °C
|
5 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IFN-γ Antibody
|
2-8 °C
|
5 vial
(5 plate size)
|
|
|
|
TURBO-BOOST Human IL-17A Antibody
|
2-8 °C
|
5 vial
(5 plate size)
|
|
|
|
S-PLEX Multiplex, 96-Well SECTOR Plate
|
2-8 °C
|
25 each
(1 each)
|
|
|
|
|
2-8 °C
|
5 bottle
(50 mL)
|
|
|
|
|
2-8 °C
|
5 bottle
(40 mL)
|
|
|
|
|
RT
|
5 bottle
(90 mL)
|
|
|
|
S-PLEX Enhance E1
|
≤-10 °C
|
25 each
(1.7 mL)
|
|
|
|
S-PLEX Enhance E2
|
≤-10 °C
|
25 vial
(1.7 mL)
|
|
|
|
S-PLEX Enhance E3
|
≤-70 °C
|
25 each
(50 μL)
|
|
|
|
|
≤-10 °C
|
5 vial
(500 μL)
|
|
|
|
Blocker S2
|
≤-10 °C
|
5 vial
(500 μL)
|
|
|
|
Product Inserts
|
|
|
|
Certificate of analysis
|
|
|
|
SDS
|
|
|
|
Title
|
Journal
|
Year
|
|
Twenty-eight day repeated exposure of human 3D bronchial epithelial model to heated tobacco aerosols indicates decreased toxicological responses compared to cigarette smoke
|
|
|
|
A phase 1 study of prophylactic anakinra to mitigate ICANS in patients with large B-cell lymphoma
|
|
|
|
Viral Antigen and Inflammatory Biomarkers in Cerebrospinal Fluid in Patients With COVID-19 Infection and Neurologic Symptoms Compared With Control Participants Without Infection or Neurologic Symptoms
|
|
|
|
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations
|
|
|
|
Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection
|
|
|
|
|
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|
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