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S-PLEX Human GFAP Kit

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S-PLEX is MSD’s ultrasensitive assay platform. It can dramatically improve the sensitivity of immunoassays, reducing the lower limit of detection (LLOD) by 10- to 1000-fold over other assay methods. The S-PLEX Human GFAP Assay has the essential components for an ultrasensitive assay that measures GFAP in a single-analyte format. For detailed instructions on running the GFAP assay, please see the product insert in the "Documentation" tab below.

Related Key Terms:
Glial fibrillary acidic protein, ALXDRD, astrocytes, cytoskeleton structure, blood-brain barrier, Down's syndrome, depression, traumatic brain injury, neurodegeneration, stroke

Specifications
Kit Contents
Documentation
References

Application(s)		Neurobiology/Neurodegeneration
Analyte(s)		GFAP
Species		Human
Instrument(s)		SECTOR Imager 2400 , MESO QuickPlex SQ 120MM , MESO SECTOR S 600 , SECTOR Imager 6000 , MESO SECTOR S 600MM , MESO QuickPlex SQ 120
Plate Type		96-well
Capture Antibody		Mouse monoclonal
Detection Antibody		Mouse monoclonal
LLOD (Sensitivity)		150 fg/mL
Dynamic Range		150 - 1,100,000 fg/mL
Sample Type		Serum, Plasma, Cell Culture Supernatant, CSF
Usage Statement		For Research Use Only. Not for use in diagnostic procedures.
Storage Condition		Multi-Component
Gene ID(s)		2670
UniProt ID(s)		P14136
Schedule B Code		3822.19.0000

Kit Contents for Catalog No. K151AMPS-1

Product Description	Storage	Quantity per Kit
S-PLEX Neurology Panel 1 (human) Calibrator Blend	≤-70 °C	1 vial (1 vial)

S-PLEX Neurology Panel 1 (human) Coating Solution	≤-70 °C	1 vial (1 vial)

S-PLEX Detect D2	≤-70 °C	1 each (50 μL)

S-PLEX Detect D1	≤-70 °C	1 each (1.7 mL)

TURBO-BOOST Human GFAP Antibody	2-8 °C	1 vial (1 plate size)

S-PLEX Multiplex, 96-Well SECTOR Plate	2-8 °C	1 each (1 each)

Diluent 100	2-8 °C	1 bottle (50 mL)

Diluent 64	2-8 °C	1 bottle (18 mL)

MSD GOLD Read Buffer B	RT	1 bottle (18 mL)

S-PLEX Enhance E1	≤-10 °C	1 each (1.7 mL)

S-PLEX Enhance E2	≤-10 °C	1 vial (1.7 mL)

S-PLEX Enhance E3	≤-70 °C	1 each (50 μL)

Blocker S1	≤-10 °C	1 vial (500 μL)

Blocker S2	≤-10 °C	1 vial (500 μL)

Kit Contents for Catalog No. K151AMPS-2

Product Description	Storage	Quantity per Kit
S-PLEX Neurology Panel 1 (human) Calibrator Blend	≤-70 °C	5 vial (1 vial)

S-PLEX Neurology Panel 1 (human) Coating Solution	≤-70 °C	5 vial (1 vial)

S-PLEX Detect D2	≤-70 °C	5 each (50 μL)

S-PLEX Detect D1	≤-70 °C	5 each (1.7 mL)

TURBO-BOOST Human GFAP Antibody	2-8 °C	1 vial (5 plate size)

S-PLEX Multiplex, 96-Well SECTOR Plate	2-8 °C	5 each (1 each)

Diluent 100	2-8 °C	1 bottle (50 mL)

Diluent 64	2-8 °C	1 bottle (90 mL)

MSD GOLD Read Buffer B	RT	1 bottle (90 mL)

S-PLEX Enhance E1	≤-10 °C	5 each (1.7 mL)

S-PLEX Enhance E2	≤-10 °C	5 vial (1.7 mL)

S-PLEX Enhance E3	≤-70 °C	5 each (50 μL)

Blocker S1	≤-10 °C	1 vial (500 μL)

Blocker S2	≤-10 °C	1 vial (500 μL)

Kit Contents for Catalog No. K151AMPS-4

Product Description	Storage	Quantity per Kit
S-PLEX Neurology Panel 1 (human) Calibrator Blend	≤-70 °C	25 vial (1 vial)

S-PLEX Neurology Panel 1 (human) Coating Solution	≤-70 °C	25 vial (1 vial)

S-PLEX Detect D2	≤-70 °C	25 each (50 μL)

S-PLEX Detect D1	≤-70 °C	25 each (1.7 mL)

TURBO-BOOST Human GFAP Antibody	2-8 °C	5 vial (5 plate size)

S-PLEX Multiplex, 96-Well SECTOR Plate	2-8 °C	25 each (1 each)

Diluent 100	2-8 °C	5 bottle (50 mL)

Diluent 64	2-8 °C	5 bottle (90 mL)

MSD GOLD Read Buffer B	RT	5 bottle (90 mL)

S-PLEX Enhance E1	≤-10 °C	25 each (1.7 mL)

S-PLEX Enhance E2	≤-10 °C	25 vial (1.7 mL)

S-PLEX Enhance E3	≤-70 °C	25 each (50 μL)

Blocker S1	≤-10 °C	5 vial (500 μL)

Blocker S2	≤-10 °C	5 vial (500 μL)

Order Details

Catalog No

Size

Price in USD

Qty

K151AMPS-1

1 plate size

$2,118.00

Not Applicable

K151AMPS-2

5 plate size

$9,007.00

Not Applicable

K151AMPS-4

25 plate size

$39,703.00

Not Applicable

Contact Information

Customer Service/Orders
1-240-314-2795

5:00 a.m. to 8:00 p.m.
US Eastern Time

Email

Scientific/Technical Support
1-240-314-2798

5:30 a.m. to 5:30 p.m.
US Eastern Time

Email

Instrument Support
1-301-947-2057

8:30 a.m. - 5:30 p.m.
US Eastern Time

Email

Company Headquarters
1-240-314-2600
1601 Research Blvd.
Rockville, Maryland 20850-3173
USA

Product Inserts		S-PLEX Neurology Panel 1 Insert
Product Highlights		S-PLEX Neurology Product Highlights
Certificate of analysis		K00S0211 K00S0198 K00S0215 K00S0157 K00S0158 K00S0159
SDS		Diluent 50, Diluent 56, Diluent 61, Diluent 100, and Diluent 101 Diluent 57, Diluent 58, and Diluent 59 MSD GOLD Read Buffer B

Title	Journal	Year
Plasma biomarkers for diagnosis of Alzheimer’s disease and prediction of cognitive decline in individuals with mild cognitive impairment Pia Kivisäkk, Thadryan Sweeney, Becky C. Carlyle, Bianca A. Trombetta, Kathryn LaCasse, Leena El-Mufti, Idil Tuncali, Lori B. Chibnik, Sudeshna Das, Clemens R. Scherzer, Keith A. Johnson, Bradford C. Dickerson, Teresa Gomez-Isla, Deborah Blacker, Derek H. Oakley, Matthew P. Frosch, Bradley T. Hyman, Anahit Aghvanyan, Pradeepthi Bathala, Christopher Campbell, George Sigal, Martin Stengelin, Steven E. Arnold	Frontiers in Neurology	2023
Elevation of neural injury markers in patients with neurologic sequelae after hospitalization for SARS-CoV-2 infection Michail Spanos, Sigal Shachar, Thadryan Sweeney, H Immo Lehmann, Priyanka Gokulnath, Guoping Li, George B Sigal, Rajini Nagaraj, Pradeepthi Bathala, Farhan Rana, Ravi V Shah, David A Routenberg, Saumya Das	iScience	2022

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S-PLEX Human GFAP Kit

Kit Contents for Catalog No. K151AMPS-1

Kit Contents for Catalog No. K151AMPS-2

Kit Contents for Catalog No. K151AMPS-4

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