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The R-PLEX platform offers matched sets of antibodies and calibrators for a wide menu of biomarkers. The R-PLEX Human IRS-1 Antibody Set can be used with other MSD components (see "Recommended Components" tab below) to build assays that measure IRS-1. These assays can measure IRS-1 alone or in multiplex panels with other biomarkers.
The Product Inserts for R-PLEX Antibody Sets provide detailed instructions for building assays in several formats. The Datasheet for IRS-1 provides lot specific information for the components (including calibrator stock concentrations), recommended sample types and dilution factors, and representative data for analytical performance. These items and other helpful documents can be found in the "Documentation" tab below.
Related Key Terms
Metabolic Diseases, Insulin Receptor Substrate 1, IRS-1
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Specifications
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Recommended Components
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Kit Contents
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Documentation
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References
Application(s)
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Metabolic
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Analyte(s)
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IRS-1
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Species
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Human
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Antibody set (2-8°C); Calibrator (≤-70°C)
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Gene ID(s)
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3667
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UniProt ID(s)
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P35568
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Why do I need other components
Catalog No.
Product Name
Size
R50JA-4
R60AM-1
L45SA-1
Product Description
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Storage
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Quantity per Kit
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Human IRS-1 Antibody Set
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2-8 °C
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1 each (5 plate size)
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Human IRS-1 Calibrator
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≤-70 °C
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5 vial (1 vial)
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Product Inserts
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Datasheets
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Handouts
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SDS
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Title
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Journal
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Year
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Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition.
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Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase.
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Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth.
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Efficacy of Ganitumab (AMG 479), Alone and in Combination With Rapamycin, in Ewing's and Osteogenic Sarcoma Models.
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Chronic treatment with epoxyeicosatrienoic acids modulates insulin signaling and prevents insulin resistance in hepatocytes.
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View All
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Order Details
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