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The R-PLEX platform offers both antibody sets and assays for a wide menu of biomarkers. The R-PLEX Human HSP27/HspB1 Assay has the essential components to build an assay that measures HSP27/HspB1 in a single analyte format. For information on multiplexing HSP27/HspB1 with other analytes, please see the
R-PLEX Human HSP27/HspB1 Antibody Set.
The Product Insert for R-PLEX Assays provides detailed instructions for building a singleplex assay. The datasheet for Human HSP27/HspB1 provides information on the components (including calibrator stock concentration), recommended sample types and dilution factors, and representative data for analytical performance. These items and other helpful documents can be found in the "Documentation" tab below.
Related Key Termsheat shock protein 27, heat shock protein beta-1, SRP27
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Specifications
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Kit Contents
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Documentation
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References
Application(s)
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Muscle Injury
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Toxicology
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Analyte(s)
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HSP27/HspB1
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Species
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Human
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Instrument(s)
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SECTOR Imager 2400
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MESO QuickPlex SQ 120MM
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MESO SECTOR S 600
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SECTOR Imager 6000
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MESO SECTOR S 600MM
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MESO QuickPlex SQ 120
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Plate Type
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96-well
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LLOD (Sensitivity)
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4.5 pg/mL
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Condition
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Multi-Component
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Gene ID(s)
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3315
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UniProt ID(s)
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P04792
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Schedule B Code
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3822.19.0000
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Product Description
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Storage
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Quantity per Kit
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Human HSP27/HspB1 Antibody Set
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2-8 °C
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1 each (5 plate size)
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Human HSP27/HspB1 Calibrator
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≤-70 °C
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5 vial (1 vial)
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2-8 °C
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5 each (1 plate)
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2-8 °C
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1 bottle (50 mL)
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≤-10 °C
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2 bottle (50 mL)
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RT
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1 bottle (90 mL)
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Product Inserts
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Datasheets
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Handouts
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SDS
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Title
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Journal
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Year
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Safety, tolerability, pharmacokinetics, and pharmacodynamics of Losmapimod following a single intravenous or oral dose in healthy volunteers.
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ERK activation by GM-CSF reduces effectiveness of p38 inhibitor on inhibiting TNFalpha release.
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A Randomized, Placebo-Controlled Study of the Effects of the p38 MAPK Inhibitor SB-681323 on Blood Biomarkers of Inflammation in COPD Patients.
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Analysis of mechanistic pathway models in drug discovery: p38 pathway.
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Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes.
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