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Tau is a microtubule-associated protein with multiple spliceoforms found primarily in neurons. Hyperphosphorylated tau is the major component of paired helical filaments and other large intracellular aggregates in the brains of patients with Alzheimer's disease and some other neurodegenerative disorders. This kit provides assay-specific components for the quantitative determination of both natural and recombinant human and mouse total tau in cerebrospinal fluid (CSF), brain homogenates, and tissue cultere supernatants.
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Specifications
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Documentation
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References
Application(s)
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Alzheimer’s Disease
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Phosphoproteins
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Neurobiology/Neurodegeneration
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Intracellular Signaling
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Analyte(s)
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Tau (total)
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Species
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Bovine, Human, Mouse
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Instrument(s)
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SECTOR Imager 2400
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MESO SECTOR S 600MM
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SECTOR Imager 6000
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MESO QuickPlex SQ 120MM
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MESO QuickPlex SQ 120
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MESO SECTOR S 600
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Plate Type
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96-well
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LLOD (Sensitivity)
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0.035 ng/mL
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Dynamic Range
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0.035-1000 ng/mL
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Usage Statement
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For Research Use Only. Not for use in diagnostic procedures.
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Storage Statement(s)
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Please refer to the product insert for the storage conditions of individual kit components.
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Storage Condition
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Multi-Component
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Schedule B Code
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3822.19.0000
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Product Inserts
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Datasheets
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SDS
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Title
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Journal
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Year
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Plasma biomarkers for diagnosis of Alzheimer’s disease and prediction of cognitive decline in individuals with mild cognitive impairment
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Changes in Amyloid-β and Tau in the Cerebrospinal Fluid of Transgenic Mice Overexpressing Amyloid Precursor Protein.
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High apolipoprotein E in cerebrospinal fluid of patients with Lewy body disorders is associated with dementia.
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Immunomodulation targeting of both Aβ and tau pathological conformers ameliorates Alzheimer's disease pathology in TgSwDI and 3xTg mouse models.
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The AD-CSF-Index discriminates Alzheimer's disease patients from healthy controls: A validation study
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View All
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