Metabolic U-PLEX Assays

U-PLEX: MSD Launches NEW Metabolic Assays

 

Metabolic-Related Research Applications

The complex pathologies of diabetes, cardiovascular disease, and metabolic syndrome have driven an increased demand for quantitative measurement of biomarkers associated with these disease states. Obesity is directly related to increased risk for diabetes, hypertension, atherosclerosis, and metabolic syndrome. Novel proteomic technologies have helped define key serum biomarkers produced in the gut and adipose tissue and altered in abundance in disease states.

MSD provides solutions to support and simplify your metabolic research needs. We offer singleplex and multiplex assays to measure biomarkers such as GLP-1, glucagon, insulin, and leptin, in a variety of formats.

U-PLEX: MSD’s Most Flexible Assay Platform

The flexibility of the U-PLEX platform empowers you to make personalized multiplex assay combinations. Now you can build and run your multiplex assay at your convenience without any additional equipment or time-consuming assay development.

Discover new combinations with the quality and performance you expect from MSD.

For Research Use Only. Not for use in diagnostic procedures.

 

U-PLEX Assay Designer

Use the U-PLEX Assay Designer to create custom panels from a selection of MSD assays, your own antibodies, or a combination of both. Choose 96- or 384-well formats.



U-PLEX Combinations for Metabolic Research

U-PLEX Combinations represent popular combinations of assays, grouped into separate catalog numbers for ordering convenience.

Species Name Catalog Number Assays
Human Diabetes Combo 1 K15274K C‑Peptide, GIP (total), GLP‑1 (total), Glucagon, Insulin, Leptin, PYY (total)
Human Diabetes Combo 2 K15275K C‑Peptide, GIP (total), GLP‑1 (active), Glucagon, Insulin, Leptin, PYY (total)
Human Adipokine Combo 1 K15276K BDNF, β‑NGF, IL‑1β, IL‑6, IL‑8, IL‑10, Insulin, Leptin, MCP‑1, TNF‑α
Human Obesity Combo 1 K15277K BDNF, FGF‑21, Ghrelin (total), Glucagon, Leptin
Human Obesity Combo 2 K15278K C‑Peptide, FGF‑23, Ghrelin (total), GLP‑1 (total), Insulin, Leptin, PYY (total)
Human Microbiome Combo 1 K15441K NEW Ghrelin (total), GLP‑1 (total), Glucagon, Insulin, Leptin, PP, PYY (total)
Human Metabolic Combo 1 K15281K BAFF, BDNF, β‑NGF, C‑Peptide, FGF‑21, FGF‑23, FSH, Ghrelin (active), Ghrelin (total), GIP (active), GIP (inactive), GIP (total), GLP‑1 (active), GLP‑1 (inactive), GLP‑1 (total), Glucagon, Insulin, Leptin, LH, PP, Proinsulin, PYY (total)
Human Metabolic Group 1 K15280K BAFF, BDNF, β NGF, C Peptide, CTACK (CCL27), ENA 78 (CXCL5), Eotaxin (CCL11), Eotaxin 2 (CCL24), Eotaxin 3 (CCL26), EPO, FGF 21, FGF 23, FLT3L, FSH, Fractalkine (CX3CL1), G CSF, Ghrelin (active), Ghrelin (total), GIP (active), GIP (inactive), GIP (total), GLP 1 (active), GLP 1 (inactive), GLP 1 (total), Glucagon, GM CSF, GRO α (CXCL1), I 309 (CCL1), IFN α2a, IFN β, IFN γ, IL 1α, IL 1β, IL 1RA, IL 2, IL 2Rα, IL 3, IL 4, IL 5, IL 6, IL 7, IL 8 (CXCL8), IL 9, IL 10, IL 12/IL 23p40, IL 12p70, IL 13, IL 15, IL 16, IL 17A, IL 17A/F, IL 17C, IL 17D, IL 17E/IL 25, IL 17F, IL 18, IL 21, IL 22, IL 23, IL 27, IL 29/IFN λ1, IL 31, IL 33, Insulin, IP 10 (CXCL10), Leptin, LH, MCP 1 (CCL2), MCP 2 (CCL8), MCP 4 (CCL13), M CSF, MDC (CCL22), MIF, MIP 1α (CCL3), MIP 5, PP, Proinsulin, PYY (total), SDF 1α (CXCL12), TARC (CCL17), TNF α, TNF β, TPO, TRAIL, TSLP, VEGF A, YKL 40
Mouse Adipokine Combo 1 K15299K BDNF, IL-1β, IL-6, IL-10, Insulin, Leptin, MCP-1, TNF-α
Mouse Diabetes Combo 1 K15298K C-Peptide, GLP-1 (total), Glucagon, Insulin, Leptin, PYY (total)
Mouse Gut Hormone Combo 1 K15307K Ghrelin (active), GLP-1 (active), Glucagon, Insulin, Leptin, PYY (total)
Mouse Metabolic 2-Plex Combo 1 K15302K Leptin, Insulin
Mouse Metabolic 2-Plex Combo 2 K15303K Insulin, Glucagon
Mouse Metabolic 3-Plex Combo 1 K15304K GLP-1 (total), Glucagon, Insulin
Mouse Metabolic 3-Plex Combo 2 K15305K GLP-1 (active), Glucagon, Insulin
Mouse Metabolic Combo 1 K15297K BDNF, C-Peptide, FGF-21, Ghrelin (active), Ghrelin (total), GLP-1 (active), GLP-1 (inactive), GLP-1 (total), Glucagon, Insulin, Leptin, PYY (total), BAFF
Mouse Metabolic Group 1 K15317K BAFF, BCA-1/BLC, BDNF, CD40, C-Peptide, Eotaxin, EPO, FGF-21, Ghrelin (active), Ghrelin (total), GLP-1 (active), GLP-1 (inactive), GLP-1 (total), Glucagon, GM-CSF, IFN-α, IFN-β, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, IL-17A/F, IL-17C, IL-17E/IL-25, IL-17F, IL-21, IL-22, IL-23, IL-27p28/IL-30, IL-31, IL-33, Insulin, IP-10, KC, Leptin, MCP-1, MCP-5/CCL12, MDC, MIP-1α, MIP-1β, MIP-2, MIP-3α, MMP-9 (total), PYY (total), RANTES, TARC, TNF-α, VEGF-A
Mouse Metabolic Hormone Combo 1 K15306K C-Peptide , Ghrelin (active), GLP-1 (active), Glucagon, IL-6, Insulin, Leptin, MCP-1, PYY (total), TNF-α
Mouse Obesity Combo 1 K15300K BDNF, FGF-21, Ghrelin (total), Glucagon, Leptin
Mouse Obesity Combo 2 K15301K C-Peptide, Ghrelin (total), GLP-1 (total), Insulin, Leptin, PYY (total)
Rat Diabetes Combo 1 K15309K C-Peptide, GLP-1 (total), Glucagon, Insulin, Leptin, PYY (total)
Rat Metabolic 2-Plex Combo 1 K15312K Leptin, Insulin
Rat Metabolic 2-Plex Combo 2 K15313K Insulin, Glucagon
Rat Metabolic 3-Plex Combo 1 K15314K GLP-1 (total), Glucagon, Insulin
Rat Metabolic 3-Plex Combo 2 K15315K GLP-1 (active), Glucagon, Insulin
Rat Metabolic Combo 1 K15308K BDNF, C-Peptide, FGF-21, Ghrelin (active), Ghrelin (total), GLP-1 (active), GLP-1 (inactive), GLP-1 (total), Glucagon, Insulin, Leptin, PYY (total)
Rat Metabolic Hormone Combo 1 K15316K C-Peptide , Ghrelin (active), GLP-1 (active), Glucagon, Insulin, Leptin, PYY (total)
Rat Obesity Combo 1 K15310K BDNF, FGF-21, Ghrelin (total), Glucagon, Leptin
Rat Obesity Combo 2 K15311K C-Peptide, Ghrelin (total), GLP-1 (total), Insulin, Leptin, PYY (total)

NEW Metabolic-Related Assays

Individual assays can be configured into customized multiplex combinations of your choice in either 96- or 384-well formats.

Combine MSD assays with your own assays or R-PLEX Antibody Sets for a truly custom multiplex.


Additional assays that are compatible with the above assays are available on the U-PLEX platform.
View our complete portfolio here.