Cytokines and chemokines are small signaling proteins secreted primarily by immune cells. Their main function is to coordinate cell growth, proliferation, and differentiation. Cytokines and their receptors participate in a diverse array of functions including innate and adaptive immunity, inflammation, immune cell differentiation, angiogenesis, tumorigenesis, development, neurobiology, and viral pathogenesis. Dysregulation of cytokine expression is a cause of immunological and inflammatory diseases, as well as other disease conditions. Many different cell types secrete chemokines, most often to attract immune cells to the site of infection or injury during innate and adaptive immune responses.

 

MSD offers an extensive portfolio of singleplex and multiplex assays to support your cytokine and chemokine research needs.