Cardiac injury is the disruption of normal cardiac myocyte membrane integrity resulting in the release of intracellular cytosolic and structural proteins such as troponin, creatine kinase, myoglobin, heart-type fatty acid binding protein, and lactate dehydrogenase into the extracellular space (e.g. blood). Causes of cardiac injury include trauma, toxins, and viral infection, but ischemia or infarction is the most common cause. Injury is usually considered irreversible.

 

MSD provides solutions to support and simplify your cardiac injury research needs. We offer assays and reagents to measure biomarkers such as cTroponin and FABP3.

• Human

Title	Journal	Year
Twenty-eight day repeated exposure of human 3D bronchial epithelial model to heated tobacco aerosols indicates decreased toxicological responses compared to cigarette smoke Fiona Chapman, Sarah Jean Pour, Roman Wieczorek, Edgar Trelles Sticken, Jessica Budde, Karin Röwer, Sandra Otte, Elizabeth Mason, Lukasz Czekala, Thomas Nahde, Grant O’Connell, Liam Simms and Matthew Stevenson	Frontiers in Toxicology	2023