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U-PLEX TH17 Combo 1 (mouse)

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U-PLEX Combos offer popular panels of biomarkers that have been grouped together for convenient ordering. They have been tested for multiplex compatibility and are fulfilled as a kit. The U-PLEX TH17 Combo 1 (mouse) combines 9 biomarkers associated with the Th17 pathway into a single assay (Table 1). The assays can be used for quantitative measurements in the sample types listed in the "Specifications" tab below, and offer detection limits (LLODs) in the sub- to low pg/mL range.

Note:This Combo is provided on 2 plates to separate incompatible assays.

Table 1. List of analytes and typical detection limits

Analyte	LLOD - ULOD	units
IL-17A	0.30 - 2,150	pg/mL
IL-17C	2.3 - 45,600	pg/mL
IL-17E/IL-25	1.6 - 18,900	pg/mL
IL-17F	24 - 52,600	pg/mL
IL-21	6.5 - 40,600	pg/mL
IL-22	1.2 - 1,850	pg/mL
IL-23	4.9 - 20,400	pg/mL
IL-31	45 - 66,200	pg/mL
IL-33	2.2 - 36,000	pg/mL

Specifications
Kit Contents
Documentation
References

Application(s)		Cytokines & Chemokines , Immunology/Inflammation
Analyte(s)		IL-17A, IL-17C, IL-17E/IL-25, IL-17F, IL-21, IL-22, IL-23, IL-31, IL-33
Species		Mouse
Plate Type		96-well
U-PLEX Group Compatibility		Biomarker Group 1
Instrument(s)		MESO SECTOR S 600MM , MESO QuickPlex SQ 120MM , MESO QuickPlex Q 60MM , MESO SECTOR S 600 , MESO QuickPlex SQ 120 , SECTOR Imager 6000 , SECTOR Imager 2400
Sample Type		Serum, Plasma, Cell Culture Supernatant
Usage Statement		For Research Use Only. Not for use in diagnostic procedures.
Storage Statement(s)		Please refer to the product insert for the storage conditions of individual kit components.
Storage Condition		Multi-Component
Schedule B Code		3822.19.0000

Kit Contents for Catalog No. K15077K-1

Product Description

Storage

Quantity per Kit

Mouse Th17 Combo 1, Box 1 of 2

Multi-Component

1 each
(1 plate size)

U-PLEX Linker Set, 6-Assay (300 µL)	2-8 °C	1 each (1 vial)
U-PLEX Mouse IL-17A Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX Mouse IL-17E/IL-25 Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX Mouse IL-21 Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX Mouse IL-23 Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX Mouse IL-22 Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX Mouse IL-17C Antibody Set	2-8 °C	1 each (1 plate size)
Calibrator 7	2-8 °C	1 vial (1 vial)
U-PLEX 6-Assay, 96-Well SECTOR Plate	2-8 °C	1 each (1 plate)
Diluent 41	≤-10 °C	1 bottle (10 mL)
Diluent 45	≤-10 °C	1 bottle (8 mL)
U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)
MSD GOLD Read Buffer B	RT	1 bottle (18 mL)

Mouse Th17 Combo 1, Box 2 of 2

Multi-Component

1 each
(1 plate size)

U-PLEX Linker Set, 3-Assay (300 µL)	2-8 °C	1 each (1 vial)
U-PLEX Mouse IL-17F Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX Mouse IL-31 Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX Mouse IL-33 Antibody Set	2-8 °C	1 each (1 plate size)
Calibrator 8	2-8 °C	1 vial (1 vial)
U-PLEX 3-Assay, 96-Well SECTOR Plate	2-8 °C	1 each (1 plate)
Diluent 41	≤-10 °C	1 bottle (10 mL)
Diluent 45	≤-10 °C	1 bottle (8 mL)
MSD GOLD Read Buffer B	RT	1 bottle (18 mL)

Kit Contents for Catalog No. K15077K-2

Product Description

Storage

Quantity per Kit

Mouse Th17 Combo 1, Box 1 of 2

Multi-Component

1 each
(5 plate size)

U-PLEX Linker Set, 6-Assay (1.8 mL)	2-8 °C	1 each (1 vial)
U-PLEX Mouse IL-17A Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX Mouse IL-17E/IL-25 Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX Mouse IL-21 Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX Mouse IL-23 Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX Mouse IL-22 Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX Mouse IL-17C Antibody Set	2-8 °C	1 each (5 plate size)
Calibrator 7	2-8 °C	5 vial (1 vial)
U-PLEX 6-Assay, 96-Well SECTOR Plate	2-8 °C	5 each (1 plate)
Diluent 41	≤-10 °C	1 bottle (50 mL)
Diluent 45	≤-10 °C	1 bottle (40 mL)
U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)
MSD GOLD Read Buffer B	RT	1 bottle (90 mL)

Mouse Th17 Combo 1, Box 2 of 2

Multi-Component

1 each
(5 plate size)

U-PLEX Linker Set, 3-Assay (1.8 mL)	2-8 °C	1 each (1 vial)
U-PLEX Mouse IL-17F Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX Mouse IL-31 Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX Mouse IL-33 Antibody Set	2-8 °C	1 each (5 plate size)
Calibrator 8	2-8 °C	5 vial (1 vial)
U-PLEX 3-Assay, 96-Well SECTOR Plate	2-8 °C	5 each (1 plate)
Diluent 41	≤-10 °C	1 bottle (50 mL)
Diluent 45	≤-10 °C	1 bottle (40 mL)
U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)
MSD GOLD Read Buffer B	RT	1 bottle (90 mL)

Kit Contents for Catalog No. K15077K-4

Product Description

Storage

Quantity per Kit

Mouse Th17 Combo 1, Box 1 of 2

Multi-Component

1 each
(5 plate size)

U-PLEX Linker Set, 6-Assay (1.8 mL)	2-8 °C	5 each (1 vial)
U-PLEX Mouse IL-17A Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX Mouse IL-17E/IL-25 Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX Mouse IL-21 Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX Mouse IL-23 Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX Mouse IL-22 Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX Mouse IL-17C Antibody Set	2-8 °C	5 each (5 plate size)
Calibrator 7	2-8 °C	25 vial (1 vial)
U-PLEX 6-Assay, 96-Well SECTOR Plate	2-8 °C	25 each (1 plate)
Diluent 41	≤-10 °C	5 bottle (50 mL)
Diluent 45	≤-10 °C	5 bottle (40 mL)
U-PLEX Stop Solution	2-8 °C	5 bottle (40 mL)
MSD GOLD Read Buffer B	RT	5 bottle (90 mL)

Mouse Th17 Combo 1, Box 2 of 2

Multi-Component

1 each
(5 plate size)

U-PLEX Linker Set, 3-Assay (1.8 mL)	2-8 °C	5 each (1 vial)
U-PLEX Mouse IL-17F Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX Mouse IL-31 Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX Mouse IL-33 Antibody Set	2-8 °C	5 each (5 plate size)
Calibrator 8	2-8 °C	25 vial (1 vial)
U-PLEX 3-Assay, 96-Well SECTOR Plate	2-8 °C	25 each (1 plate)
Diluent 41	≤-10 °C	5 bottle (50 mL)
Diluent 45	≤-10 °C	5 bottle (40 mL)
U-PLEX Stop Solution	2-8 °C	5 bottle (40 mL)
MSD GOLD Read Buffer B	RT	5 bottle (90 mL)

Kit Contents for Catalog No. K15077K-21

Product Description	Storage	Quantity per Kit
U-PLEX Mouse Th17 Combo 1 (1 Plt) Box 1 of 2	Multi-Component	1 each (1 each)

U-PLEX Mouse Th17 Combo 1 (1 Plt) Box 2 of 2	Multi-Component	1 each (1 each)

Kit Contents for Catalog No. K15077K-22

Product Description	Storage	Quantity per Kit
U-PLEX Mouse Th17 Combo 1, Box 1 of 2 (5 PL)	Multi-Component	1 each (5 each)

U-PLEX Mouse Th17 Combo 1, Box 2 of 2 (5 PL)	Multi-Component	1 each (5 each)

Kit Contents for Catalog No. K15077K-24

Product Description	Storage	Quantity per Kit
U-PLEX Mouse Th17 Combo 1, Box 1 of 2 (25 PL)	Multi-Component	1 each (25 each)

U-PLEX Mouse Th17 Combo 1, Box 2 of 2 (25 PL)	Multi-Component	1 each (25 each)

Order Details

K15077K

Select your instrument:

S 600

SQ 120

Q 60

Catalog No

Size

Price in USD

Qty

K15077K-1

1 plate size

$1,983.00

Usually ships in 1-3 days

K15077K-2

5 plate size

$8,427.00

Usually ships in 1-3 days

K15077K-4

25 plate size

$37,921.00

Usually ships in 1-3 days

K15077K-21

1 plate size

$1,983.00

Usually ships in 1-3 days

K15077K-22

5 plate size

$8,427.00

Usually ships in 1-3 days

K15077K-24

25 plate size

$37,921.00

Usually ships in 1-3 days

Customize

Contact Information

Meso Scale Japan 株式会社
電話: (050) 1706-7074
〒103-0027
東京都中央区日本橋三丁目９番１号日本橋三丁目スクエア 11階 Vistra　Japan内

Product Inserts		U-PLEX Biomarker Group 1 (mouse) Multiplex Insert
Datasheets		U-PLEX Mouse IL-17A U-PLEX Mouse IL-17C U-PLEX Mouse IL-17E/IL-25 U-PLEX Mouse IL-17F U-PLEX Mouse IL-21 U-PLEX Mouse IL-22 U-PLEX Mouse IL-23 View More
Product Highlights		U-PLEX Platform Highlights
SDS		Biotin-conjugated Antibodies Safety Data Sheet Diluent 41, Diluent 43 and Diluent 45 MSD Calibrators and Controls MSD GOLD Read Buffer B U-PLEX Linker Set

Title	Journal	Year
Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection Najmeh Bozorgmehr, Siavash Mashhouri, Eliana Perez Rosero, Lai Xu, Shima Shahbaz, Wendy Sligl, Mohammed Osman, Demetrios J. Kutsogiannis, Erika MacIntyre, Conar R. O’Neil, Shokrollah Elahi	mBio	2021
Reliability of self-sampling for accurate assessment of respiratory virus viral and immunologic kinetics Alpana Waghmare, Elizabeth M Krantz, Subhasish Baral, Emma Vasquez, Tillie Loeffelholz, E. Lisa Chung, Urvashi Pandey, Jane Kuypers, Elizabeth R Duke, Keith R Jerome, Alexander L Greninger, Daniel B Reeves, Florian Hladik, E Fabian Cardozo-Ojeda, Michael Boeckh, Joshua T Schiffer	TBD	2020
Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease-associated psychological morbidity Bain KA, McDonald E, Moffat F, Tutino M, Castelino M, Barton A, Cavanagh J, Ijaz UZ, Siebert S, McInnes IB, Astrand A, Holmes S, Milling SWF	British Journal of Dermatology	2019
Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial G B Sigal, M R Segal, A Mathew, L Jarlsberg, M Wang, S Barbero, N Small, K Haynesworth, J L Davis, M Weiner, W C Whitworth, J Jacobs, J Schorey, D M Lewinsohn, P Nahid	EBioMedicine	2017
Stratum Corneum Tape Stripping: Monitoring of Inflammatory Mediators in Atopic Dermatitis Patients Using Topical Therapy. Koppes SA, Brans R, Ljubojevic Hadzavdic S, Frings-Dresen MH, Rustemeyer T, Kezic S.	Int Arch Allergy Immunol.	2016
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U-PLEX TH17 Combo 1 (mouse)

Kit Contents for Catalog No. K15077K-1

Kit Contents for Catalog No. K15077K-2

Kit Contents for Catalog No. K15077K-4

Kit Contents for Catalog No. K15077K-21

Kit Contents for Catalog No. K15077K-22

Kit Contents for Catalog No. K15077K-24

Order Details

K15077K

S 600

SQ 120

Q 60

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