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U-PLEX Macrophage M2 Combo 1 (mouse)

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U-PLEX Combos offer popular panels of biomarkers that have been grouped together for convenient ordering. They have been tested for multiplex compatibility and are fulfilled as a kit. The U-PLEX Macrophage M2 Combo 1 (mouse) combines assays for 5 macrophage biomarkers (Table 1). The assays can be used for quantitative measurements in the sample types listed in the "Specifications" tab below, and offer detection limits (LLODs) in the sub- to low pg/mL range.

Table 1. List of analytes and typical detection limits

Analyte	LLOD - ULOD	units
IL-4	0.56 - 10,000	pg/mL
IL-10	3.8 - 22,800	pg/mL
IL-13	2.7 - 22,800	pg/mL
MDC	13 - 10,000	pg/mL
TARC	0.32 - 1,200	pg/mL

Specifications
Kit Contents
Documentation
References

Application(s)		Cytokines & Chemokines , Immunology/Inflammation
Analyte(s)		IL-4, IL-10, IL-13, MDC, TARC
Species		Mouse
Instrument(s)		SECTOR Imager 2400 , MESO QuickPlex SQ 120MM , MESO SECTOR S 600 , SECTOR Imager 6000 , MESO SECTOR S 600MM , MESO QuickPlex SQ 120
U-PLEX Group Compatibility		Biomarker Group 1
Plate Type		96-well
Sample Type		Cell Culture Supernatant, EDTA Plasma, Plasma
Usage Statement		For Research Use Only. Not for use in diagnostic procedures.
Storage Statement(s)		Please refer to the product insert for the storage conditions of individual kit components.
Storage Condition		Multi-Component
Schedule B Code		3822.19.0000

Product Description	Storage	Quantity per Kit
U-PLEX Linker Set, 5-Assay (300 µL)	2-8 °C	1 each (1 vial)

U-PLEX Mouse TARC Antibody Set	2-8 °C	1 each (1 plate size)

U-PLEX Mouse IL-4 Antibody Set	2-8 °C	1 each (1 plate size)

U-PLEX Mouse IL-10 Antibody Set	2-8 °C	1 each (1 plate size)

U-PLEX Mouse IL-13 Antibody Set	2-8 °C	1 each (1 plate size)

U-PLEX Mouse MDC Antibody Set	2-8 °C	1 each (1 plate size)

Calibrator 5	2-8 °C	1 vial (1 vial)

Calibrator 16	≤-70 °C	1 vial (1 vial)

Calibrator 17	2-8 °C	1 vial (1 vial)

U-PLEX 5-Assay, 96-Well SECTOR Plate	2-8 °C	1 each (1 plate)

Diluent 41	≤-10 °C	1 bottle (10 mL)

Diluent 45	≤-10 °C	1 bottle (8 mL)

U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)

MSD GOLD Read Buffer B	RT	1 bottle (18 mL)

Product Description	Storage	Quantity per Kit
U-PLEX Linker Set, 5-Assay (1.8 mL)	2-8 °C	1 each (1 vial)

U-PLEX Mouse TARC Antibody Set	2-8 °C	1 each (5 plate size)

U-PLEX Mouse IL-4 Antibody Set	2-8 °C	1 each (5 plate size)

U-PLEX Mouse IL-10 Antibody Set	2-8 °C	1 each (5 plate size)

U-PLEX Mouse IL-13 Antibody Set	2-8 °C	1 each (5 plate size)

U-PLEX Mouse MDC Antibody Set	2-8 °C	1 each (5 plate size)

Calibrator 5	2-8 °C	5 vial (1 vial)

Calibrator 16	≤-70 °C	5 vial (1 vial)

Calibrator 17	2-8 °C	5 vial (1 vial)

U-PLEX 5-Assay, 96-Well SECTOR Plate	2-8 °C	5 each (1 plate)

Diluent 41	≤-10 °C	1 bottle (50 mL)

Diluent 45	≤-10 °C	1 bottle (40 mL)

U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)

MSD GOLD Read Buffer B	RT	1 bottle (90 mL)

Product Description	Storage	Quantity per Kit
U-PLEX Linker Set, 5-Assay (1.8 mL)	2-8 °C	5 each (1 vial)

U-PLEX Mouse TARC Antibody Set	2-8 °C	5 each (5 plate size)

U-PLEX Mouse IL-4 Antibody Set	2-8 °C	5 each (5 plate size)

U-PLEX Mouse IL-10 Antibody Set	2-8 °C	5 each (5 plate size)

U-PLEX Mouse IL-13 Antibody Set	2-8 °C	5 each (5 plate size)

U-PLEX Mouse MDC Antibody Set	2-8 °C	5 each (5 plate size)

Calibrator 5	2-8 °C	25 vial (1 vial)

Calibrator 16	≤-70 °C	25 vial (1 vial)

Calibrator 17	2-8 °C	25 vial (1 vial)

U-PLEX 5-Assay, 96-Well SECTOR Plate	2-8 °C	25 each (1 plate)

Diluent 41	≤-10 °C	5 bottle (50 mL)

Diluent 45	≤-10 °C	5 bottle (40 mL)

U-PLEX Stop Solution	2-8 °C	5 bottle (40 mL)

MSD GOLD Read Buffer B	RT	5 bottle (90 mL)

Title	Journal	Year
Viral Antigen and Inflammatory Biomarkers in Cerebrospinal Fluid in Patients With COVID-19 Infection and Neurologic Symptoms Compared With Control Participants Without Infection or Neurologic Symptoms Arvid Edén, Anna Grahn, Daniel Bremell, Anahit Aghvanyan, Pradeepthi Bathala, Dietmar Fuchs, Johanna Gostner, Lars Hagberg, Nelly Kanberg, Sunsanee Kanjananimmanont, Magnus Lindh, Salvia Misaghian, Staffan Nilsson, Michael Schöll, George Sigal, Erika Stentoft, Marie Studahl, Aylin Yilmaz, Mingyue Wang, Martin Stengelin, Henrik Zetterberg, Magnus Gisslén	JAMA Network Open	2022
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations Bing Sun, Norina Tang, Michael J. Peluso, Nikita S. Iyer, Leonel Torres, Joanna L. Donatelli, Sadie E. Munter, Christopher C. Nixon, Rachel L. Rutishauser, Isabel Rodriguez-Barraquer, Bryan Greenhouse, John D. Kelly, Jeffrey N. Martin, Steven G. Deeks, Timothy J. Henrich, and Lynn Pulliam	Cells	2021
Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection Najmeh Bozorgmehr, Siavash Mashhouri, Eliana Perez Rosero, Lai Xu, Shima Shahbaz, Wendy Sligl, Mohammed Osman, Demetrios J. Kutsogiannis, Erika MacIntyre, Conar R. O’Neil, Shokrollah Elahi	mBio	2021
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, Xue Manz, Jurjan Aman, Amsterdam UMC COVID-19 Biobank, Peter Bonta, Philip Brouwer, Steven de Taeye, Tom Caniels, Karlijn van der Straten, Korneliusz Golebski, Guillermo Griffith, René Jonkers, Mads Larsen, Federica Linty, Annette Neele, Jan Nouta, Frank van Baarle, Cornelis van Drunen, Alexander Vlaar, Godelieve de Bree, Rogier Sanders, Lisa Willemsen, Manfred Wuhrer, Harm Jan Bogaard, Marit van Gils, Gestur Vidarsson, Menno de Winther, Jeroen den Dunnen	TBD	2020
Multisystem inflammatory syndrome in children and COVID-19 are distinct presentations of SARS–CoV-2 Caroline Diorio, Sarah E. Henrickson, Laura A. Vella, Kevin O. McNerney, Julie Chase, Chakkapong Burudpakdee, Jessica H. Lee, Cristina Jasen, Fran Balamuth, David M. Barrett, Brenda L. Banwell, Kathrin M. Bernt, Allison M. Blatz, Kathleen Chiotos, Brian T. Fisher, Julie C. Fitzgerald, Jeffrey S. Gerber, Kandace Gollomp, Christopher Gray, Stephan A. Grupp, Rebecca M. Harris, Todd J. Kilbaugh, Audrey R. Odom John, Michele Lambert, Emily J. Liebling, Michele E. Paessler, Whitney Petrosa, Charles Phillips, Anne F. Reilly, Neil D. Romberg, Alix Seif, Deborah A. Sesok-Pizzini, Kathleen E. Sullivan, Julie Vardaro, Edward M. Behrens, David T. Teachey, Hamid Bassiri	The Journal of Clinical Investigation	2020
View All

Order Details

Catalog No

Size

Price in USD

Qty

K15409K-1

1 plate size

$1,361.00

Not Applicable

K15409K-2

5 plate size

$5,534.00

Not Applicable

K15409K-4

25 plate size

$24,393.00

Not Applicable

Contact Information

Meso Scale Japan 株式会社
電話: 03.6265.7384
〒107-0062
東京都港区南青山 1-1-1 新青山ビル西館１４階 Vistra　Japan内

Product Inserts		U-PLEX Biomarker Group 1 (mouse) Multiplex Insert
Datasheets		U-PLEX Mouse IL-4 U-PLEX Mouse IL-10 U-PLEX Mouse IL-13 DS U-PLEX Mouse MDC DS U-PLEX Mouse TARC
Product Highlights		U-PLEX Platform Highlights
SDS		Biotin-conjugated Antibodies Safety Data Sheet Diluent 41, Diluent 43 and Diluent 45 MSD Calibrators and Controls MSD GOLD Read Buffer B U-PLEX Linker Set

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U-PLEX Macrophage M2 Combo 1 (mouse)

Kit Contents for Catalog No. K15409K-1

Kit Contents for Catalog No. K15409K-2

Kit Contents for Catalog No. K15409K-4

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