The MSD GOLD SULFO-TAG Anti-Human IgG Antibody is a monoclonal antibody that binds human immunoglobulin G (IgG), serving as an effective primary or secondary detection reagent in MSD assays. MSD has implemented stringent quality control measures for MSD GOLD SULFO-TAG Anti-Human IgG Antibody to ensure lot-to-lot reproducibility, meeting the specific requirements of critical assays and longitudinal studies.

The MSD GOLD SULFO-TAG Anti-Human IgG Antibody (Catalog No. D21APR-6) is supplied at a stock concentration of 400 µg/mL.

Key Features

• Meets MSD GOLD products' rigorous specifications for lot-to-lot consistency and precision
• Recognizes all IgG subclasses and has no cross-reactivity with other immunoglobulin isotypes (IgA and IgM)
• Functionally tested to measure IgG antibody against multiple antigens in human samples relevant to COVID-19, Mpox, and respiratory viral disease research applications
• Ideal for vaccine and epidemiology studies, serology, and screening applications

The functional performance of three independent lots of MSD GOLD SULFO-TAG Anti-Human IgG Antibody was tested on 33 antigens across five V-PLEX Serology panels using a panel of serum samples (N=12-21). Representative data for the SARS-CoV-2 Spike, Mpox A35R, and HCoV-OC43 Spike antigens are shown below (Figures a, b, and c). The graphs demonstrate excellent inter-lot concordance for three MSD GOLD SULFO-TAG Anti-Human IgG Antibody lots in measuring serum IgG levels.

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Figure: Functional performance: Inter-lot concordance for three MSD GOLD SULFO-TAG Anti-Human IgG Antibody lots in measuring serum IgG levels against a) SARS-CoV-2 Spike antigen, b) Mpox virus A35R antigen, and c) Human Coronavirus (HCoV) OC43 Spike antigen.