Calibrator 1 is a lyophilized blend of 14 recombinant human proteins: GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-13, IL-17A, TNF-α, and VEGF-A. It was developed for use as an assay calibrator for MSD U-PLEX human and non-human primate assays that measure any of the included proteins. The utility of this product has not been evaluated in other applications. Individual analyte concentrations are provided in the lot-specific certificates of analysis. Calibrator 1 includes GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-13, IL-17A, and TNF-α expressed in E. coli, and IL-5, IL-10, IL-12p70, and VEGF-A expressed in insect cells. The instructions on using Calibrator 1 in U-PLEX assays are provided in U-PLEX Biomarker Group 1 Human Product Inserts and U-PLEX Biomarker Group 1 NHP Product Inserts.

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