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Discovery of diverse and functional antibodies from large human repertoire antibody libraries.
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Dual blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) pathways synergistically inhibits rhabdomyosarcoma cell growth in vitro and in vivo.
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Functional Consequences of the Macrophage Stimulating Protein 689C Inflammatory Bowel Disease Risk Allele.
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Multimodal microvascular imaging reveals that selective inhibition of class I PI3K is sufficient to induce an antivascular response.
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S49076 is a novel kinase inhibitor of MET, AXL and FGFR with strong preclinical activity alone and in association with bevacizumab.
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