| References | Journal | Year | |
Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice.
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Piperidine-derived gamma-secretase modulators.
Hall, A., Elliott, R.L., Giblin, G.M., Hussain, I., Musgrave, J., Naylor, A., Sasse, R., Smith, B. | Bioorg Med Chem Lett | 2010 | View |
Placental growth factor neutralising antibodies give limited anti-angiogenic effects in an in vitro organotypic angiogenesis model.
Brave, S.R., Eberlein, C., Shibuya, M., Wedge, S.R., Barry, S.T. | Angiogenesis. | 2010 | View |
Polyphenol-enriched apple extract attenuates food allergy in mice.
Zuercher, A.W., Holvoet, S., Weiss, M., Mercenier, A. | Clin Exp Allergy. | 2010 | View |
Postnatal PPARd Activation and Myostatin Inhibition Exert Distinct yet Complimentary Effects on the Metabolic Profile of Obese Insulin-Resistant Mice.
Bernardo, B.L., Wachtmann, T.S., Cosgrove, P.G., Kuhn, M., Opsahl, A.C., Judkins, K.M., Freeman, T.B., Hadcock, J.R., LeBrasseur, N.K. | PLoS One | 2010 | View |
Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis.
Lazar-Molnar, E., Chen, B., Sweeney, K.A., Wang, E.J., Liu, W., Lin, J., Porcelli, S.A., Almo, S.C., Nathenson, S.G., Jacobs, W.R. Jr. | Proc Natl Acad Sci USA. | 2010 | View |
Purinergic receptor-mediated morphological changes in microglia are transient and independent from inflammatory cytokine release.
McIlvain, H.B., Ma, L., Ludwig, B., Manners, M.T., Martone, R.L., Dunlop, J., Kaftan, E.J., Kennedy, J.D., Whiteside, G.T. | Eur J Pharmacol. | 2010 | View |
RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.
Hatzivassiliou, G., Song, K., Yen, I., Brandhuber, B.J., Anderson, D.J., Alvarado, R., Ludlam, M.J., Stokoe, D., Gloor, S.L., Vigers, G., Morales, T., Aliagas, I., Liu, B., Sideris, S., Hoeflich, K.P., Jaiswal, B.S., Seshagiri, S., Koeppen, H., Belvin, M., Friedman, L.S., Malek, S. | Nature. | 2010 | View |
Rapamycin Pharmacokinetic and Pharmacodynamic Relationships in Osteosarcoma: A Comparative Oncology Study in Dogs.
Paoloni, M.C., Mazcko, C., Fox, E., Fan, T., Lana, S., Kisseberth, W., Vail, D.M., Nuckolls, K., Osborne, T., Yalkowsy, S., Gustafson, D., Yu, Y., Cao, L., Khan, C. | PLoS ONE | 2010 | View |
Rapid Cerebral Amyloid Binding by Abeta Antibodies Infused into beta-Amyloid Precursor Protein Transgenic Mice.
Winkler, D.., Abramowski, D., Danner, S., Zurini, M., Paganetti, P., Tolnay, M., Staufenbiel, M. | Biol Psychiatry. | 2010 | View |
Recommendations to qualify biomarker candidates of drug-induced liver injury.
Ozer, J.S., Chetty, R., Kenna, G., Koppiker, N., Karamjeet, P., Li, D., Palandra, J., Lanevschi, A., Souberbielle, B.E., Ramaiah, S. | Biomark Med. | 2010 | View |
Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease.
Paris, D., Ganey, N.J., Laporte, V., Patel, N.S., Beaulieu-Abdelahad, D., Bachmeier, C., March, A., Ait-Ghezala, G., Mullan, M.J. | J Neuroinflammation. | 2010 | View |
Repeat tuberculin skin testing leads to desensitisation in naturally infected tuberculous cattle which is associated with elevated interleukin-10 and decreased interleukin-1 beta responses.
Coad, M., Clifford, D., Rhodes, S.G., Hewinson, R.G., Vordermeier, H.M., Whelan, A.O. | Vet Res. | 2010 | View |
Response of Th17 cells to a citrullinated arthritogenic aggrecan peptide in patients with rheumatoid arthritis.
von Delwig, A., Locke, J., Robinson, J.H., Ng, W.F. | Arthritis Rheum. | 2010 | View |
Rheumatoid factor interference in immunogenicity assays for human monoclonal antibody therapeutics.
Tatarewicz, S., Miller, J.M., Swanson, S.J., Moxness, M.S. | Journal of Immunological Methods | 2010 | View |
Rho-kinase mediates lysophosphatidic acid-induced IL-8 and MCP-1 production via p38 and JNK pathways in human endothelial cells.
Shimada, H., Rajagopalan, L.E. | FEBS Lett. | 2010 | View |
Rose hip exerts anti-diabetic effects via a mechanism involving downregulation of the hepatic lipogenic program.
Andersson, U., Henriksson, E., Strom, K., Alenfall, J., Goransson, O., Holm, C. | Am J Physiol Endocrinol Metab. | 2010 | View |
Safety, pharmacokinetics, and pharmacodynamics of AMG 102, a fully human hepatocyte growth factor-neutralizing monoclonal antibody, in a first-in-human study of patients with advanced solid tumors.
Gordon, M.S., Sweeney, C.S., Mendelson, D.S., Eckhardt, S.G., Anderson, A., Beaupre, D.M., Branstetter, D., Burgess, T.L., Coxon, A., Deng, H., Kaplan-Lefko, P., Leitch, I.M., Oliner, K.S., Yan, L., Zhu, M., Gore, L. | Clin Cancer Res. | 2010 | View |
Selective and potent raf inhibitors paradoxically stimulate normal cell proliferation and tumor growth.
Carnahan, J., Beltran, P.J., Babij, C., Le, Q., Rose, M.J., Vonderfecht, S., Kim, J.L., Smith, A.L., Nagapudi, K., Broome, M.A., Fernando, M., Kha, H., Belmontes, B., Radinsky, R., Kendall, R., Burgess, T.L. | Mol Cancer Ther. | 2010 | View |
Sequestration of the Aß Peptide Prevents Toxicity and Promotes Degradation In Vivo.
Luheshi, L.M., Hoyer, W., de Barros, T.P., Hard, I.V., Brorsson, A., Macao, B., Persson, C., Crowther, D.C., Lomas, D.A., Stahl, S., Dobson, C.M., Hard, T. | PLoS Biol. | 2010 | View |
Serum correlates of the placebo effect in irritable bowel syndrome.
Kokkotou, E., Conboy, L.A., Ziogas, D.C., Quilty, M.T., Kelley, J.M., Davis, R.B., Lembo, A.J., Kaptchuk, T.J. | Neurogastroenterol Motil. | 2010 | View |
Serum levels of a subset of cytokines show high interindividual variability and are not altered in rats transgenic for Huntington´s disease.
Nguyen, H.P., Bjorkqvist, M., Bode, F.J., Stephan, M., von Horsten, S. | PLoS Curr. | 2010 | View |
Sex and ethnic differences in 47 candidate proteomic markers of cardiovascular disease: the mayo clinic proteomic markers of arteriosclerosis study.
Kim, C.X., Bailey, K.R., Klee, G.G., Ellington, A.A., Liu, G., Mosley, T.H. Jr, Rehman, H., Kullo, I.J. | Cancer Chemother Pharmacol. | 2010 | View |
Shorter dosing intervals of sublingual immunotherapy lead to more efficacious treatment in a mouse model of allergic inflammation.
Rask, C , Brimnes, J., Lund, K. | Scandinavian Journal of Immunology. | 2010 | View |
Short-term IL-1beta blockade reduces monocyte CD11b integrin expression in an IL-8 dependent fashion in patients with type 1 diabetes.
Sanda, S., Bollyky, J., Standifer, N., Nepom, G., Hamerman, J.A., Greenbaum, C. | Clin Immunol. | 2010 | View |