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Discovery of LY2457546: a multi-targeted anti-angiogenic kinase inhibitor with a novel spectrum of activity and exquisite potency in the acute myelogenous leukemia-Flt-3-internal tandem duplication mutant human tumor xenograft model.
Burkholder, T.P., Clayton, J.R., Rempala, M.E., Henry, J.R., Knobeloch, J.M., Mendel, D., McLean, J.A., Hao, Y., Barda, D.A., Considine, E.L., Uhlik, M.T., Chen, Y., Ma, L., Bloem, L.J., Akunda, J.K., McCann, D.J., Sanchez-Felix, M., Clawson, D.K., Lahn, M.M., Starling, J.J. | Invest New Drugs. | 2011 | View |
Domain-based assays of individual antibody concentrations in an oligoclonal combination targeting a single protein.
Meng, Q., Li, M., Silberg, M.A., Conrad, F., Bettencourt, J., To, R., Huang, C., Ma, J., Meyer, K., Shimizu, R., Cao, L., Tomic, M.T., Marks, J.D. | Anal Biochem. | 2011 | View |
Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth.
Gao, J., Chesebrough, J.W., Cartlidge, S.A., Ricketts, S.A., Incognito, L., Veldman-Jones, M., Blakey, D.C., Tabrizi, M., Jallal, B., Trail, P.A., Coats, S., Bosslet, K., Chang, Y.S. | Cancer Res. | 2011 | View |
Duodenal-jejunal bypass protects GK rats from {beta}-cell loss and aggravation of hyperglycemia and increases enteroendocrine cells coexpressing GIP and GLP-1.
Speck, M., Cho, Y.M., Asadi, A., Rubino, F., Kieffer, T.J. | Am J Physiol Endocrinol Metab. | 2011 | View |
Early postnatal blood concentrations of inflammation-related proteins and microcephaly two years later in infants born before the 28th post-menstrual week.
Leviton, A., Kuban, K.C., Allred, E.N., Fichorova, R.N., O'Shea, T.M., Paneth, N.; for the ELGAN Study Investigators. | Early Hum Dev. | 2011 | View |
Effects of peripherally administered neuromedin U on energy and glucose homeostasis.
Peier, A.M., Desai, K., Hubert, J., Du, X., Yang, L., Qian, Y., Kosinski, J.R., Metzger, J.M., Pocai, A., Nawrocki, A.R., Langdon, R.B., Marsh, D.J. | Endocrinology | 2011 | View |
Efficacy of Ganitumab (AMG 479), Alone and in Combination With Rapamycin, in Ewing's and Osteogenic Sarcoma Models.
Beltran, P.J., Chung, Y.A., Moody, G., Mitchell, P., Cajulis, E., Vonderfecht, S., Kendall, R., Radinsky, R., Calzone, F.J. | Pharmacol Exp Ther. | 2011 | View |
Endothelial dysfunction and low-grade inflammation are associated with greater arterial stiffness over a 6-year period.
van Bussel, B.C., Schouten, F., Henry, R.M., Schalkwijk, C.G., de Boer, M.R., Ferreira, I., Smulders, Y.M., Twisk, J.W., Stehouwer, C.D. | Hypertension. | 2011 | View |
Enhanced humoral and cell-mediated immune responses after immunization with trivalent influenza vaccine adjuvanted with cationic liposomes.
Rosenkrands, I., Vingsbo-Lundberg, C., Bundgaard, T.J., Lindenstrøm, T., Enouf, V., van der Werf, S., Andersen, P., Agger, E.M. | Vaccine. | 2011 | View |
Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype.
McKernan, D.P., Dennison, U., Gaszner, G., Cryan, J.F., Dinan, T.G. | Translational Psychiatry | 2011 | View |
Eosinophil and neutrophil extracellular DNA traps in human allergic asthmatic airways.
Dworski, R., Simon, H.U., Hoskins, A., Yousefi, S. | J Allergy Clin Immunol. | 2011 | View |
E-Selectin is Elevated in Cord Blood of South Asian Neonates Compared with Caucasian Neonates.
Boon MR, Karamali NS, de Groot CJ, van Steijn L, Kanhai HH, van der Bent C, Berbée JF, Middelkoop B, Rensen PC, Tamsma JT. | J Pediatr. | 2011 | View |
Essential Role for Protein Kinase C{zeta} in Oleic Acid-Induced Glucagon-Like Peptide-1 Secretion in Vivo in the Rat.
Iakoubov, R., Ahmed, A., Lauffer, L.M., Bazinet, R.P., Brubaker, P.L. | Endocrinology | 2011 | View |
Evaluation of KRAS mutations, angiogenic biomarkers and DCE-MRI in patients with advanced non-small cell lung cancer receiving sorafenib.
Kelly, R.J., Rajan, A., Force, J., Keen, C., Cao, L., Yu, Y., Choyke, P.L., Turkbey, B., Raffeld, M., Xi, L., Steinberg, S.M., Wright, J.J., Lopez-Chavez, A., Kummar, S., Guttierrez, M., Giaccone, G. | Clin Cancer Res. | 2011 | View |
Evidence for Elevated Cerebrospinal Fluid ERK1/2 Levels in Alzheimer Dementia.
Spitzer, P., Scheib, H., Kamrowski-Kruck, H, Otto, M., Chiasserini, D., Parnetti, L., Herukka, S.K., Schuchhart, J., Wiltfang, J., Klafki, H.W. | International Journal of Alzheimer's Disease. | 2011 | View |
Exchanging Saturated Fatty Acids for (n-6) Polyunsaturated Fatty Acids in a Mixed Meal May Decrease Postprandial Lipemia and Markers of Inflammation and Endothelial Activity in Overweight Men.
Masson, C.J., Mensink, R.P. | J Nutr. | 2011 | View |
Experimental endotoxemia induces leukocyte adherence and plasma extravasation within the rat pial microcirculation.
Zhou, J., Schmidt, M., Johnston, B., Wilfart, F., Whynot, S., Hung, O., Murphy, M., Cerny, V., Pavlovic, D., Lehmann, C. | Physiol Res. | 2011 | View |
Exploratory analysis of early toxicity of sunitinib in advanced hepatocellular carcinoma patients: kinetics and potential biomarker value.
Zhu, A.X., Duda, D.G., Ancukiewicz, M., di Tomaso, E., Clark, J.W., Miksad, R., Fuchs, C.S., Ryan, D.P., Jain, R.K. | Clin Cancer Res. | 2011 | View |
Factors influencing the degradation of archival formalin-fixed paraffin-embedded tissue sections.
Xie, R., Chung, J.Y., Ylaya, K., Williams, R.L., Guerrero, N., Nakatsuka, N., Badie, C., Hewitt, S.M. | J Histochem Cytochem. | 2011 | View |
Familial aggregation of autoimmune disease in juvenile dermatomyositis.
Niewold, T.B., Wu, S.C., Smith, M., Morgan, G.A., Pachman, L.M. | Pediatrics | 2011 | View |
Fate of Transgenic DNA from Orally Administered Bt MON810 Maize and Effects on Immune Response and Growth in Pigs.
Walsh, M.C., Bouzuianu, S.G., Gardiner, G.E., Rea, M.C., Gelencser, E., Janosi, A., Epstein, M.M., Ross, R.P., Lawlor, P.G. | PLoS One. | 2011 | View |
Fetal exposure to chlordane and permethrin mixtures in relation to inflammatory cytokines and birth outcomes.
Neta G, Goldman LR, Barr D, Apelberg BJ, Witter FR, Halden RU. | Environ Sci Technol. | 2011 | View |
Fetal-placental inflammation, but not adrenal activation, is associated with extreme preterm delivery.
Trivedi S, Joachim M, McElrath T, Kliman HJ, Allred EN, Fichorova RN, Onderdonk A, Heitor F, Chaychi L, Leviton A, Majzoub JA; ELGAN study investigators. | Am J Obstet Gynecol. | 2011 | View |
Fish oil supplementation alters levels of lipid mediators of inflammation in microenvironment of acute human wounds.
McDaniel, J.C., Massey, K., Nicolaou, A. | Wound Repair Regen. | 2011 | View |
Functionalized Scaffold-mediated Interleukin 10 Gene Delivery Significantly Improves Survival Rates of Stem Cells In Vivo.
Holladay, C., Power, K., Sefton, M., O'Brien, T., Gallagher, W.M., Pandit, A. | Mol Ther. | 2011 | View |