| References | Journal | Year | |
Neuroprotective effect of Pycnogenol® following traumatic brain injury.
Scheff SW, Ansari MA, Roberts KN. | Exp Neurol. | 2012 | View |
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase.
Talukdar S, Oh DY, Bandyopadhyay G, Li D, Xu J, McNelis J, Lu M, Li P, Yan Q, Zhu Y, Ofrecio J, Lin M, Brenner MB, Olefsky JM. | Nat Med. | 2012 | View |
Nociceptin/orphanin FQ inhibition with SB612111 ameliorates dextran sodium sulfate-induced colitis.
Alt C, Lam JS, Harrison MT, Kershaw KM, Samuelsson S, Toll L, D'Andrea A. | Eur J Pharmacol. | 2012 | View |
Novel Biological Action of the Dipeptidylpeptidase-IV Inhibitor, Sitagliptin, as a Glucagon-Like Peptide-1 Secretagogue.
Sangle GV, Lauffer LM, Grieco A, Trivedi S, Iakoubov R, Brubaker PL. | Endocrinology. | 2012 | View |
Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation.
Xing S, Bhat S, Shroff NS, Zhang H, Lopez JA, Margolick JB, Liu JO, Siliciano RF. | J Antimicrob Chemother. | 2012 | View |
Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: A randomized controlled trial.
Kiecolt-Glaser JK, Belury MA, Andridge R, Malarkey WB, Hwang BS, Glaser R. | Brain Behav Immun. | 2012 | View |
Open-heart surgery increases cerebrospinal fluid levels of Alzheimer-associated amyloid β.
Reinsfelt B, Westerlind A, Blennow K, Zetterberg H, Ricksten SE. | Acta Anaesthesiol Scand. | 2012 | View |
Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes.
Scadding GW, Calderon MA, Bellido V, Koed GK, Nielsen NC, Lund K, Togias A, Phippard D, Turka LA, Hansel TT, Durham SR, Wurtzen PA. | J Immunol Methods. | 2012 | View |
Overcoming soluble target interference in an anti-therapeutic antibody screening assay for an antibody-drug conjugate therapeutic.
Carrasco-Triguero M, Mahood C, Milojic-Blair M, Amaya C, Ruppel J, Hong K, Yi JH, Kaur S. | Bioanalysis. | 2012 | View |
Pancortins interact with amyloid precursor protein and modulate cortical cell migration.
Rice HC, Townsend M, Bai J, Suth S, Cavanaugh W, Selkoe DJ, Young-Pearse TL. | Development. | 2012 | View |
Performance of a multi-biomarker score measuring rheumatoid arthritis disease activity in the CAMERA tight control study.
Bakker MF, Cavet G, Jacobs JW, Bijlsma JW, Haney DJ, Shen Y, Hesterberg LK, Smith DR, Centola M, van Roon JA, Lafeber FP, Welsing PM. | Ann Rheum Dis. | 2012 | View |
Pharmacokinetic and pharmacodynamic analysis of circulating biomarkers of anti-NRP1, a novel anti-angiogenesis agent, in two phase I trials in patients with advanced solid tumors.
Xin Y, Li J, Wu J, Kinard R, Weekes CD, Patnaik A, Lorusso PM, Brachmann R, Tong RK, Yan Y, Watts R, Bai S, Hegde PS. | Clin Cancer Res. | 2012 | View |
Pharmacokinetic and pharmacodynamic comparability study of moxetumomab pasudotox, an immunotoxin targeting CD22, in cynomolgus monkeys.
Wang B, Liang M, Yao Z, Vainshtein I, Lee R, Schneider A, Zusmanovich M, Jin F, O'Connor K, Donato-Weinstein B, Iciek L, Lavallee T, Roskos L. | J Pharm Sci. | 2012 | View |
Pharmacokinetics and biodistribution of a human monoclonal antibody to oxidized LDL in cynomolgus monkey using PET imaging.
Kamath AV, Williams SP, Bullens S, Cowan KJ, Stenberg Y, Cherry SR, Rendig S, Kukis DL, Griesemer C, Damico-Beyer LA, Bunting S. | PLoS One | 2012 | View |
Pharmacokinetics and Pharmacodynamics of Figitumumab, a Monoclonal Antibody Targeting the Insulin-Like Growth Factor 1 Receptor, in Healthy Participants.
Yin D, Sleight B, Alvey C, Hansson AG, Bello A. | J Clin Pharmacol. | 2012 | View |
Pharmacological inhibition of diacylglycerol acyltransferase 1 reduces body weight and modulates gut peptide release – potential insight into mechanism of action.
Liu J, Gorski J, Gold SJ, Chen D, Chen S, Forrest G, Itoh Y, Marsh D, McLaren D, Shen Z, Sonatore L, Carballo-Jane E, Craw S, Guan X, Karanam B, Sakaki J, Szeto D, Tong X, Xiao J, Yoshimoto R, Yu H, Balkovec J, Pinto S. | Obesity | 2012 | View |
Pharmacologically Dosed Oral Glutamine Reduces Myocardial Injury in Patients Undergoing Cardiac Surgery: A Randomized Pilot Feasibility Trial.
Sufit A, Weitzel LB, Hamiel C, Queensland K, Dauber I, Rooyackers O, Wischmeyer PE. | J Parenter Enteral Nutr. | 2012 | View |
Phase 1, open-label study of MEDI-547 in patients with relapsed or refractory solid tumors.
Annunziata CM, Kohn EC, Lorusso P, Houston ND, Coleman RL, Buzoianu M, Robbie G, Lechleider R. | Invest New Drugs. | 2012 | View |
Phase 1 study of ganitumab (AMG 479), a fully human monoclonal antibody against the insulin-like growth factor receptor type I (IGF1R), in Japanese patients with advanced solid tumors.
Murakami H, Doi T, Yamamoto N, Watanabe J, Boku N, Fuse N, Yoshino T, Ohtsu A, Otani S, Shibayama K, Takubo T, Loh E. | Cancer Chemother Pharmacol. | 2012 | View |
Phase 1b dose-finding study of motesanib with docetaxel or paclitaxel in patients with metastatic breast cancer.
De Boer RH, Kotasek D, White S, Koczwara B, Mainwaring P, Chan A, Melara R, Ye Y, Adewoye AH, Sikorski R, Kaufman PA. | Breast Cancer Res Treat. | 2012 | View |
Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer.
Pienta KJ, Machiels JP, Schrijvers D, Alekseev B, Shkolnik M, Crabb SJ, Li S, Seetharam S, Puchalski TA, Takimoto C, Elsayed Y, Dawkins F, de Bono JS. | Invest New Drugs. | 2012 | View |
Phase I clinical trial of mixed bacterial vaccine (Coley's toxins) in patients with NY-ESO-1 expressing cancers: Immunological effects and clinical activity.
Karbach J, Neumann A, Brand K, Wahle C, Siegel E, Maeurer M, Ritter E, Tsuji T, Gnjatic S, Old LJ, Ritter G, Jäger E. | Clin Cancer Res. | 2012 | View |
Phase I Study of Cetuximab, Irinotecan, and Vandetanib (ZD6474) as Therapy for Patients with Previously Treated Metastastic Colorectal Cancer.
Meyerhardt JA, Ancukiewicz M, Abrams TA, Schrag D, Enzinger PC, Chan JA, Kulke MH, Wolpin BM, Goldstein M, Blaszkowsky L, Zhu AX, Elliott M, Regan E, Jain RK, Duda DG. | PLoS One. | 2012 | View |
Phase II Study of Bevacizumab in Patients With HIV-Associated Kaposi's Sarcoma Receiving Antiretroviral Therapy.
Uldrick TS, Wyvill KM, Kumar P, O'Mahony D, Bernstein W, Aleman K, Polizzotto MN, Steinberg SM, Pittaluga S, Marshall V, Whitby D, Little RF, Yarchoan R. | J Clin Oncol. | 2012 | View |
Physiological and behavioural responsivity to stress and anxiogenic stimuli in COMT-deficient mice.
Desbonnet L, Tighe O, Karayiorgou M, Gogos JA, Waddington JL, O'Tuathaigh CM. | Behav Brain Res. | 2012 | View |