U-PLEX Immuno-Oncology Assays

New U-PLEX Immuno-Oncology Assays  

Immuno-Oncology Research Applications

Great strides have been made in the field of cancer research as a result of harnessing native and modified cells of the immune system. Therapies using genetically modified T-cells have proven to be effective against certain hematologic malignancies. Antibodies that bind to checkpoint ligands and receptors have immensely increased the effectiveness of drug treatments and cell therapies against many types of cancers.

Discover new combinations with the quality and performance you expect from MSD.

For Research Use Only. Not for use in diagnostic procedures.
  U-PLEX Assay Designer

Use the U-PLEX Assay Designer to create custom multiplex assays from a selection of MSD assays, your own antibodies, or a combination of both.

U-PLEX Combinations for Immuno-Oncology Research

U-PLEX Combos represent popular combinations of assays, grouped into separate catalog numbers for ordering convenience.

Species Name Catalog Number Assays
Human Angiogenesis Combo 1 K15339K FGF (basic), PlGF, Tie‑2, VEGF‑A, VEGF‑D
Human CAR-T Cell Combo 1 K15338K GM‑CSF, Granzyme A, Granzyme B, IFN‑γ, IL‑2, TNF‑α
Human CAR-T Cell Combo 2 K15600K GM‑CSF, Granzyme A, Granzyme B, IFN‑γ, IL‑2, Perforin, TNF‑α
Human CAR-T Cell Efficacy Combo 1 K15709K NEW Granzyme B, IFN‑γ, IL‑2, IL-6, IL-12p70, IP-10, Perforin, TNF‑α
Human CAR-T Cell Exhaustion Combo 1 K15710K NEW CD28, CTLA4, IFN-γ, LAG3, PD-L1 (epitope 1), TIGIT, TNF-α
Human CAR-T Cell Persistence Combo 1 K15708K NEW CD40L, Granzyme B, IFN-γ, IL-7, IL-15, IL-18, LAG3, PD-L1 (epitope 1), TNF-α
Human CAR-T Cell Safety Combo 1 K15711K NEW GM-CSF, IFN-γ, IL-1β, IL-6, IL-10, MCP-1, TNF-α
Human Effector Cell Checkpoint Combo 1 K15341K CD27, CD28, CD40L (soluble), CTLA‑4, GITR/TNFRSF18, HAVCR2/TIM‑3, LAG3, OX40/TNFRSF4, PD1 (epitope 1), TIGIT
Human Macrophage M1 Combo 1 K15336K IL-1β, IL-6, IL-12p70, IL-18, IL-23, IP-10, MCP-1, MIP-1α, TNF-α
Human Macrophage M2 Combo 1 K15337K Eotaxin-2, IL-4, IL-10, IL-13, M-CSF, MDC, TARC
Human Metastasis Combo 1 K15602K E-Selectin, MMP-1, MMP-2, MMP-7, MMP-9 (total), P-Selectin, VEGFR-1/Flt-1
Human Oncolysis Combo 1 K15603K CTLA-4, IFN-α2a, IFN-β, IL-1α, IL-2Rα, IL-6, IL-8, IP-10, LAG3, MIP-1α, PD1, TIGIT, TNF-α
Human Target Cell Checkpoint Combo 1 K15340K CD276/B7‑H3, GITRL/TNFSF18, PD‑L1 (epitope 1), PD‑L2
Mouse Macrophage M1 Combo 1 K15408K IL-1β, IL-6, IL-12p70, IL-15, IL-23, IP-10, MCP-1, MIP-1α, TNF-α
Mouse Macrophage M2 Combo 1 K15409K IL-4, IL-10, IL-13, MDC, TARC

Immuno-Oncology Assays

Individual assays can be configured into customized multiplex assays of your choice in either 96- or 384-well plates.

Combine MSD assays with your own assays or with R-PLEX Antibody Sets for a truly custom multiplex.

Description Catalog Number
4-1BBL/TNFSF9 K151AQHK
APRIL/TNFSF13 K151AGUK
BAFF-R/TNFRSF13C K151K7K
BCMA/TNFRSF17 K151D8K
BTLA K151AQQK
CD20 K151F7K
CD27 K151G7K
CD276/B7-H3 K151E7K
CD28 K151H7K
CD40/TNFRSF5 K151AQKK
CD40L (soluble) K151L7K
CD80/B7-1 K151AQRK
CTLA-4 K151R7K
E-Cadherin K151AQBK
E-Selectin K151AGVK
Fas (soluble) K151AQCK
FasL K151AQLK
FGF (basic) K151X7K
Galectin-9 K151AGWK
GITR/TNFRSF18 K151Y7K
GITRL/TNFSF18 K151S7K
gp130 (soluble) K151P7K
Granzyme A K151G8K
Granzyme B K151H8K
HAVCR1/KIM-1 K151AQMK
HAVCR2/TIM-3 K151E8K
HVEM/TNFRSF14 K151AGXK
ICOS K151AHBK
ICOS-L/B7-H2 K151AHJK
IDO-1 K151AQSK
LAG3 K151Q7K
LIGHT/TNFSF14 K151AHCK
MIG K151AGYK
Description Catalog Number
MMP-1 K151AHDK
MMP-2 K151AHKK
MMP-7 K151AHEK
MMP-8 (total) K151AQEK
MMP-9 (total) K151AHMK
MMP-10 (total) K151AQUK
Nectin-4 K151AHFK
OX40/TNFRSF4 K151T7K
PD1 (epitope 1) K151U7K
PD1 (epitope 2) K151V7K
PD-L1 (epitope 1) K151Z7K
PD-L1 (epitope 2) K151AHSK
PD-L2 K151A8K
Pentraxin 3 K151AGZK
Perforin K151AHGK
PlGF K151B8K
proMMP-8 K151AQDK
proMMP-9 K151AHLK
proMMP-10 K151AQTK
P-Selectin K151AHNK
RAGE (soluble) K151AHAK
RANKL/TNFSF11 K151M7K
RANTES K151A2K
S100A12 K151AHPK
TACI/TNFRSF13B K151AQPK
Tie-2 K151F8K
TIGIT K151W7K
TLR1 K151J7K
TNF-RI K151AHQK
TNF-RII K151AHRK
VEGF-D K151C8K
VEGFR-1/Flt-1 K151AHHK